Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942107 | 0.92 | LMNA (0.52) | ALDH1A1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8941958 | 0.89 | ALDH1A1 (0.39) | ALDH1A1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8942026 | 0.88 | ALDH1A1 (0.44) | ALDH1A1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL9775969 | 0.86 | ALDH1A1 (0.67) | ALDH1A1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8941977 | 0.84 | KMT2A (0.38) | ALDH1A1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8941986 | 0.84 | ALDH1A1 (0.38) | ALDH1A1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8942165 | 0.84 | EPHA2 (0.37) | ALDH1A1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL9147435 | 0.84 | LMNA (0.58) | ALDH1A1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8941969 | 0.84 | DPP4 (0.48) | ALDH1A1LMNACYP2C9KDM4EHPGD | |
| SCHEMBL8942224 | 0.83 | ALDH1A1 (0.48) | ALDH1A1LMNACYP2C9ATP6V1B2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |