SCHEMBL8942179

SCHEMBL8942179

O=S(=O)(Nc1ccccc1)c1ccccc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IL1RN P18510 1/20 0.55
KEAP1 Q14145 1/20 0.55
ERAP1 Q9NZ08 1/20 0.55
PTPN5 P54829 4/20 0.54
PTPN1 P18031 3/20 0.54
PTPN2 P17706 2/20 0.54
PTK2B Q14289 1/20 0.53
ACLY P53396 3/20 0.53
KDM4E B2RXH2 1/20 0.53
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
ALDH1A1 P00352 1/20 0.52
PKM P14618 1/20 0.52
HSPD1 P10809 2/20 0.51
HSPE1 P61604 2/20 0.51
TDP1 Q9NUW8 1/20 0.49
DUSP3 P51452 1/20 0.49
CASP6 P55212 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22340615 0.85 MCL1 (0.55) PTPN5PTPN1PTPN2CA1CA2
SCHEMBL7627388 0.85 KEAP1 (0.67) IL1RNKEAP1ERAP1PTPN5PTK2B
SCHEMBL4488183 0.84 TSHR (0.60) KDM4EALDH1A1TSHR
SCHEMBL13521290 0.84 PKLR (0.49) IL1RNKEAP1ERAP1PTPN5PTK2B
SCHEMBL28270284 0.81 HTR6 (0.62) PTPN5PTPN1PTPN2ACLYKDM4E
SCHEMBL29688324 0.79 CA12 (0.56) KDM4ECA1CA2KMT2AMEN1
SCHEMBL17774562 0.79 KMT2A (0.56) IL1RNKEAP1ERAP1PTK2BKDM4E
SCHEMBL9012590 0.79 KMT2A (0.56) IL1RNKEAP1ERAP1PTK2BKDM4E
SCHEMBL9996904 0.79 PFKFB3 (0.74) PTPN5PTPN1PTPN2ACLYKDM4E
SCHEMBL5968506 0.78 IL1RN (0.48) IL1RNKEAP1ERAP1PTK2BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109831916-B Compositions and methods for treating huntington's disease 沃雅戈治疗公司 2023-07-21 CN disclosed
US-20110020600-A1 Cellulose Acylate Film, Method for Producing Same, Optically Compensatory Film, Anti-Reflection Film, Polarizing Plate and Image Display Device FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20100066948-A1 OPTICAL FILM, POLARIZING PLATE, AND VA-MODE LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2010-03-18 US disclosed
US-20090317567-A1 CELLULOSE ESTER FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-12-24 US disclosed
CN-1329277-A Contrast improved photothermosensitive imaging element and its imaging method EASTMAN KODAK CO (US) 2002-01-02 CN disclosed
CN-1327173-A Image forming element containing closing compound for photograph EASTMAN KODAK CO (US) 2001-12-19 CN disclosed
CN-1164282-A Photothermographic material having high interlayer adhesion IMATION CORP (US) 1997-11-05 CN disclosed
EP-0645374-B1 5-AMINO-2-PHENOXYSULFONANILIDE COMPOUND TAISHO PHARMACEUTICAL CO LTD (JP) 1996-11-20 EP disclosed
US-5521311-A USEFUL AS ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS AND ANTI-ALLERGENIC AGENTS TAISHO PHARMACEUTICAL CO., LTD. (JP) 1996-05-28 US disclosed
EP-0685461-A1 5-AMINOACETYLAMINOSULFONANILIDE COMPOUND TAISHO PHARMACEUTICAL CO. LTD (JP) 1995-12-06 EP disclosed
US-5449826-A Antiinflammatory, antipyretic, antirheumatic, and analgesic agents TAISHO PHARMACEUTICAL CO., LTD. (JP) 1995-09-12 US disclosed
EP-0645374-A1 5-AMINO-2-PHENOXYSULFONANILIDE COMPOUND TAISHO PHARMACEUTICAL CO. LTD (JP) 1995-03-29 EP disclosed