Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TOP2A | P11388 | 3/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775925 | 0.92 | TOP2A (0.56) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL8941990 | 0.89 | LMNA (0.45) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL8942324 | 0.87 | LMNA (0.43) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL8942130 | 0.87 | LMNA (0.60) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL8942137 | 0.87 | LMNA (0.49) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL8942301 | 0.87 | LMNA (0.43) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL8942162 | 0.86 | DPP4 (0.56) | ALDH1A1KDM4EHSD17B10LMNATOP2A | |
| Water SCHEMBL8942213 | 0.85 | DPP4 (0.55) | ALDH1A1KDM4EHSD17B10LMNATOP2A | |
| SCHEMBL9775887 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL8941979 | 0.84 | DPP4 (0.50) | ALDH1A1KDM4EHSD17B10HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |