SCHEMBL8942920

SCHEMBL8942920

CC1(C)CC[C@H](O)C(=O)O1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR5 P51681 1/20 0.32
KDM4E B2RXH2 2/20 0.31
CYP19A1 P11511 2/20 0.31
TSHR P16473 2/20 0.31
POLB P06746 1/20 0.31
ATM Q13315 1/20 0.30
TP53 P04637 3/20 0.30
CYP3A4 P08684 3/20 0.30
MAPK1 P28482 3/20 0.30
HIF1A Q16665 2/20 0.30
LMNA P02545 2/20 0.30
CYP1A2 P05177 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
NFKB1 P19838 1/20 0.30
THPO P40225 1/20 0.30
PPM1B O75688 1/20 0.30
PTPN1 P18031 1/20 0.30
PPP1CC P36873 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4612224 0.79
SCHEMBL11307797 0.77 GPBAR1 (0.33) CCR5TSHRTP53CYP3A4MAPK1
SCHEMBL14275665 0.76 KDM4E (0.30) KDM4E
SCHEMBL8943039 0.75 KDM4E (0.37) KDM4ELMNASMN1; SMN2NPC1
Hydrochloric Acid SCHEMBL9068147 0.74
Hydrochloric Acid SCHEMBL9068149 0.74
SCHEMBL6356580 0.74 KDM4E (0.31) KDM4E
SCHEMBL8942935 0.72 SIRT2 (0.32)
SCHEMBL8943285 0.72 SIRT2 (0.32)
SCHEMBL8943459 0.71 L3MBTL1 (0.36) KDM4ESMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467721-B1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO (JP) 1996-03-27 EP disclosed
US-5480580-A COMPOUNDS FOR VISUAL AIDS WITH GOOD STABILITY MITSUBISHI RAYON COMPANY LTD. (JP) 1996-01-02 US disclosed
EP-0467721-A1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO., LTD (JP) 1992-01-22 EP disclosed