Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 12/20 | 0.81 |
| ▸ | HTR1A | P08908 | 6/20 | 0.78 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.60 |
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125943 | 0.90 | HTR7 (0.81) | HTR7HTR1AADRA2AADRA2BDRD2 | |
| SCHEMBL8131304 | 0.90 | HTR7 (1.00) | HTR7HTR1AADRA2AADRA2BDRD2 | |
| SCHEMBL8133693 | 0.89 | HTR7 (0.80) | HTR7HTR1AADRA2AADRA2BDRD2 | |
| SCHEMBL8128438 | 0.88 | HTR7 (1.00) | HTR7HTR1AADRA2AADRA2BDRD2 | |
| SCHEMBL7309594 | 0.87 | HTR7 (0.68) | HTR7HTR1AADRA2AADRA2BDRD2 | |
| SCHEMBL8136613 | 0.87 | HTR7 (0.76) | HTR7HTR1AADRA2AADRA2BDRD2 | |
| SCHEMBL8134874 | 0.83 | HTR7 (1.00) | HTR7HTR1AADRA2AADRA2BDRD2 | |
| SCHEMBL10637877 | 0.82 | ADRA2A (0.81) | HTR7HTR1AADRA2AADRA2BDRD2 | |
| SCHEMBL7300518 | 0.82 | HTR7 (0.77) | HTR7HTR1AADRA2AADRA2BDRD2 | |
| SCHEMBL3406831 | 0.82 | ADRA2A (0.88) | HTR7HTR1AADRA2AADRA2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576318-A | FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | BOEHRINGER INGELHEIM ITALIA S.P.A. (IT) | 1996-11-19 | — | — | US | disclosed |