Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944143 | 0.99 | EPHX1 (0.34) | ALOX5FASNEPHX1RARBALDH1A1 | |
| SCHEMBL8943262 | 0.93 | ALOX5 (0.36) | ALOX5FASNDGAT1CYP3A4CYP2C9 | |
| SCHEMBL8943366 | 0.90 | ALOX5 (0.33) | ALOX5FASNEPHX1RARBCYP3A4 | |
| SCHEMBL18718623 | 0.89 | ALOX5 (0.37) | ALOX5 | |
| SCHEMBL8943916 | 0.89 | ALOX5 (0.35) | ALOX5FASNEPHX1RARB | |
| SCHEMBL8943604 | 0.89 | RARB (0.34) | ALOX5FASNEPHX1RARBALDH1A1 | |
| SCHEMBL8943437 | 0.89 | ALOX5 (0.35) | ALOX5FASNEPHX1RARB | |
| SCHEMBL8943343 | 0.89 | ALOX5 (0.35) | ALOX5FASNEPHX1RARB | |
| SCHEMBL8943565 | 0.88 | SLC6A2 (0.37) | ALOX5 | |
| SCHEMBL8943434 | 0.88 | RARB (0.36) | ALOX5FASNEPHX1RARBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |