SCHEMBL8943375

SCHEMBL8943375

CCOC(C)(C)C(S)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RNPEP Q9H4A4 1/20 0.37
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
PTGS1 P23219 1/20 0.32
TDP1 Q9NUW8 3/20 0.31
HPGD P15428 2/20 0.31
HSD17B10 Q99714 2/20 0.31
ABCB11 O95342 1/20 0.31
F2 P00734 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALOX15 P16050 1/20 0.31
KMT2A Q03164 1/20 0.31
DUSP3 P51452 1/20 0.31
PTPN5 P54829 1/20 0.31
PTPN11 Q06124 1/20 0.31
LMNA P02545 1/20 0.31
CYP2C9 P11712 1/20 0.31
HIF1A Q16665 1/20 0.31
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28760503 0.68 PGD (0.34) TDP1ADRA1A
SCHEMBL4325459 0.68
SCHEMBL1849072 0.67 RNPEP (0.42) RNPEPALDH1A1MAPTPTGS1TDP1
SCHEMBL4676137 0.67
SCHEMBL27345525 0.67 PIN1 (0.36) RNPEPALDH1A1HSD17B10KDM4EMEN1
SCHEMBL20663427 0.67 RNPEP (0.43) RNPEPALDH1A1MAPTPTGS1TDP1
SCHEMBL9517417 0.67 TP53 (0.32) ALDH1A1TDP1KDM4ECA2MAPK1
Acetic Acid SCHEMBL9771962 0.66 FFAR3 (0.41) ALDH1A1TDP1HSD17B10KDM4EALOX15
SCHEMBL22980744 0.66
SCHEMBL9866977 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5529977-A A 3-ALKOXYBUTYRYLIMIDAZOLE COMPOUND UBE INDUSTRIES, LTD. (JP) 1996-06-25 US disclosed
US-5387575-A Pyrimidine derivatives, process for preparing the same and herbicide using the same UBE INDUSTRIES, LTD. (JP) 1995-02-07 US disclosed
EP-0517215-A1 Pyrimidine or triazine derivative, process for preparing the same and herbicide using the same UBE INDUSTRIES, LTD. (JP) 1992-12-09 EP disclosed