⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4141863 | 1.00 | — | — | |
| SCHEMBL924500 | 1.00 | — | — | |
| SCHEMBL1802277 | 1.00 | — | — | |
| SCHEMBL130804 | 0.92 | TDP1 (0.50) | — | |
| SCHEMBL129425 | 0.92 | TDP1 (0.50) | — | |
| SCHEMBL33424 | 0.92 | TDP1 (0.50) | — | |
| SCHEMBL44781 | 0.92 | TDP1 (0.50) | — | |
| SCHEMBL130805 | 0.92 | TDP1 (0.50) | — | |
| SCHEMBL12816270 | 0.92 | TDP1 (0.50) | — | |
| SCHEMBL8943002 | 0.89 | TDP1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167302-B2 | Phosphonate nucleosides useful in the treatment of viral diseases | UNIVERSITY COLLEGE CORK (IE) | 2019-01-01 | — | — | US | disclosed |
| US-20170218001-A1 | PHOSPHONATE NUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISEASES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2017-08-03 | — | — | US | disclosed |
| US-20170218001-A1 | PHOSPHONATE NUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISEASES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2017-08-03 | — | — | US | disclosed |
| WO-2015177351-A1 | PHOSPHONATE NUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISEASES | UNIVERSITY COLLEGE CORK (IE) | 2015-11-26 | — | — | WO | disclosed |
| US-7166754-B2 | Methods and compositions for enantioselective oxidation reactions | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-01-23 | — | — | US | disclosed |
| US-7166754-B2 | Methods and compositions for enantioselective oxidation reactions | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-01-23 | — | — | US | disclosed |
| EP-0614457-B1 | LEUKOTRIENE-B 4? DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS | SCHERING AG (DE) | 1996-08-21 | — | — | EP | disclosed |
| US-5502075-A | Leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| EP-0529022-B1 | NEW LEUKOTRIENE B 4? DERIVATIVES, METHOD FOR PREPARING THEM AND THEIR USE AS DRUGS | SCHERING AG (DE) | 1995-09-27 | — | — | EP | disclosed |
| US-5414016-A | New leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |
| EP-0614457-A1 | LEUKOTRIENE-B 4? DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS. | SCHERING AG (DE) | 1994-09-14 | — | — | EP | disclosed |
| WO-1993011105-A1 | LEUKOTRIENE-B4 DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-06-10 | — | — | WO | disclosed |
| EP-0529022-A1 | NEW LEUKOTRIENE B 4? DERIVATIVES, METHOD FOR PREPARING THEM AND THEIR USE AS DRUGS. | SCHERING AG (DE) | 1993-03-03 | — | — | EP | disclosed |
| WO-1992016504-A1 | NEW LEUKOTRIENE B4 DERIVATIVES, METHOD FOR PREPARING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1992-10-01 | — | — | WO | disclosed |