SCHEMBL8943436

SCHEMBL8943436

C=CC(=O)OCCn1ccc2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 4/20 0.53
CCND1 P24385 4/20 0.53
LMNA P02545 1/20 0.52
MAPK1 P28482 4/20 0.49
KMT2A Q03164 2/20 0.49
THRB P10828 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C19 P33261 1/20 0.46
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45
HSD17B10 Q99714 1/20 0.45
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
USP2 O75604 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16090993 0.82 MAPK1 (0.52) CDK4CCND1LMNAMAPK1KMT2A
SCHEMBL27452610 0.82 CDK4 (0.59) CDK4CCND1LMNAMAPK1KMT2A
SCHEMBL8163392 0.81 MAPK1 (0.60) CDK4CCND1LMNAMAPK1KMT2A
SCHEMBL3821123 0.79 MAPK1 (0.55) CDK4CCND1LMNAMAPK1KMT2A
SCHEMBL31211624 0.79 MAPK1 (0.55) CDK4CCND1LMNAMAPK1KMT2A
SCHEMBL11528658 0.77 THRB (0.49) LMNAKMT2ATHRBCYP3A4HSD17B10
SCHEMBL378868 0.75 FNTA (0.51) KMT2ATHRBCYP3A4MEN1ALDH1A1
SCHEMBL29697308 0.75 FNTA (0.51) KMT2ATHRBCYP3A4MEN1ALDH1A1
SCHEMBL29780037 0.74 MAPK1 (0.68) CDK4CCND1LMNAMAPK1KMT2A
SCHEMBL27565238 0.74 CDK4 (0.61) CDK4CCND1LMNAMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5532099-A RESIN GRAINS DISPERSED IN A NONAQUEOUS SOLVENT POLYMERIZED IN PRESENCE OF DISPERSION STABILIZING RESIN; TONER IMAGES HAVING RESIST WITH ETCHING RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1996-07-02 US claimed
US-5344694-A Liquid developer for electrostatic photography FUJI PHOTO FILM CO., LTD. (JP) 1994-09-06 US claimed
US-5589312-A RESIN GRAINS FUJI PHOTO FILM CO., LTD. (JP) 1996-12-31 US disclosed
US-5532099-A RESIN GRAINS DISPERSED IN A NONAQUEOUS SOLVENT POLYMERIZED IN PRESENCE OF DISPERSION STABILIZING RESIN; TONER IMAGES HAVING RESIST WITH ETCHING RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1996-07-02 US disclosed
US-5356748-A Nonaqueous solvent containing dispersed resin grains and graft polymer stabilizer FUJI PHOTO FILM CO., LTD. (JP) 1994-10-18 US disclosed
US-5344694-A Liquid developer for electrostatic photography FUJI PHOTO FILM CO., LTD. (JP) 1994-09-06 US disclosed