Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26032291 | 0.81 | L3MBTL1 (0.45) | L3MBTL1TP53NPC1MITFLMNA | |
| SCHEMBL16090946 | 0.81 | LMNA (0.45) | L3MBTL1TP53NPC1MITFLMNA | |
| SCHEMBL27739460 | 0.80 | L3MBTL1 (0.51) | L3MBTL1TP53NPC1MITFLMNA | |
| SCHEMBL29177490 | 0.80 | L3MBTL1 (0.51) | L3MBTL1TP53NPC1MITFLMNA | |
| SCHEMBL11525697 | 0.78 | NPC1 (0.47) | THRBL3MBTL1TP53NPC1MITF | |
| SCHEMBL8943436 | 0.77 | CDK4 (0.53) | THRBNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL11228302 | 0.76 | L3MBTL1 (0.50) | THRBL3MBTL1TP53LMNATSHR | |
| SCHEMBL9752736 | 0.75 | L3MBTL1 (0.60) | L3MBTL1TP53NPC1MITFLMNA | |
| SCHEMBL29409695 | 0.74 | MEN1 (0.66) | THRBLMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL2033572 | 0.74 | MEN1 (0.66) | THRBLMNASMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159202-A | PHOTOCOPYING | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-26 | — | — | US | disclosed |