SCHEMBL8943700

SCHEMBL8943700

COCCOCCOc1ccc(N(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.51
RECQL P46063 1/20 0.51
APP P05067 9/20 0.50
L3MBTL1 Q9Y468 2/20 0.46
HPGD P15428 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MCHR1 Q99705 1/20 0.41
MAPT P10636 2/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17500202 0.95 KDM4E (0.56) KDM4ERECQLAPPL3MBTL1MEN1
SCHEMBL8943717 0.95 L3MBTL1 (0.49) KDM4ERECQLAPPL3MBTL1HPGD
SCHEMBL498131 0.89 KDM4E (0.47) KDM4ERECQLAPPL3MBTL1ALDH1A1
SCHEMBL17879939 0.89 APP (0.59) KDM4ERECQLAPPHPGDMEN1
SCHEMBL18857636 0.88 KDM4E (0.50) KDM4ERECQLAPPL3MBTL1MAPT
SCHEMBL10002247 0.88 KDM4E (0.50) KDM4ERECQLAPPL3MBTL1MAPT
SCHEMBL16978405 0.88 KDM4E (0.50) KDM4ERECQLAPPL3MBTL1MAPT
SCHEMBL16968371 0.88 KDM4E (0.50) KDM4ERECQLAPPL3MBTL1ALDH1A1
SCHEMBL8943603 0.88 APP (0.47) KDM4ERECQLAPPL3MBTL1HPGD
SCHEMBL14174231 0.87 APP (0.60) KDM4ERECQLAPPL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed