SCHEMBL8943717

SCHEMBL8943717

COCCOc1ccc(N(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.49
MCHR1 Q99705 3/20 0.44
MAPT P10636 2/20 0.44
KDM4E B2RXH2 2/20 0.44
RECQL P46063 1/20 0.44
HPGD P15428 1/20 0.44
ATM Q13315 1/20 0.44
APP P05067 4/20 0.43
TSHR P16473 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42
DRD2 P14416 1/20 0.42
DRD4 P21917 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943700 0.95 KDM4E (0.51) L3MBTL1MCHR1MAPTKDM4ERECQL
SCHEMBL498131 0.94 KDM4E (0.47) L3MBTL1MAPTKDM4ERECQLAPP
SCHEMBL17500202 0.89 KDM4E (0.56) L3MBTL1KDM4ERECQLAPPTSHR
SCHEMBL8943762 0.88 MAPT (0.54) L3MBTL1MCHR1MAPTKDM4ERECQL
SCHEMBL12093635 0.88 CA12 (0.55) L3MBTL1MAPTKDM4EAPPALDH1A1
SCHEMBL8944175 0.87 L3MBTL1 (0.59) L3MBTL1MAPTHPGDATMTSHR
SCHEMBL8943988 0.87 L3MBTL1 (0.59) L3MBTL1MAPTHPGDATMTSHR
SCHEMBL20251336 0.87 DRD2 (0.46) L3MBTL1MAPTKDM4ERECQLTSHR
SCHEMBL12659398 0.87 L3MBTL1 (0.48) L3MBTL1MAPTKDM4ERECQLTSHR
SCHEMBL8943706 0.87 ACHE (0.56) L3MBTL1MCHR1MAPTHPGDATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed