SCHEMBL498131

SCHEMBL498131

COCCOc1ccc(N(c2ccc(OCCOC)cc2)c2ccc(OCCOC)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.47
RECQL P46063 1/20 0.47
ALDH1A1 P00352 3/20 0.42
MAPT P10636 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NQO1 P15559 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
APP P05067 5/20 0.40
TSHR P16473 1/20 0.40
RAB9A P51151 1/20 0.40
MCL1 Q07820 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17500202 0.94 KDM4E (0.56) KDM4ERECQLALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL8943717 0.94 L3MBTL1 (0.49) KDM4ERECQLALDH1A1MAPTL3MBTL1
SCHEMBL20251336 0.92 DRD2 (0.46) KDM4ERECQLMAPTL3MBTL1TSHR
SCHEMBL12659398 0.92 L3MBTL1 (0.48) KDM4ERECQLMAPTL3MBTL1TSHR
SCHEMBL16024121 0.91 CHKA (0.48) KDM4ERECQL
SCHEMBL8943700 0.89 KDM4E (0.51) KDM4ERECQLALDH1A1MAPTL3MBTL1
SCHEMBL10330364 0.88 LSS (0.50) MAPTL3MBTL1RAB9A
SCHEMBL16978405 0.88 KDM4E (0.50) KDM4ERECQLMAPTL3MBTL1APP
SCHEMBL10002247 0.88 KDM4E (0.50) KDM4ERECQLMAPTL3MBTL1APP
SCHEMBL18431945 0.88 LSS (0.50) MAPTL3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1994575-B1 LIQUID CHARGE TRANSPORTING MATERIAL ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2020-05-27 EP disclosed
EP-1994575-B1 LIQUID CHARGE TRANSPORTING MATERIAL ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2020-05-27 EP disclosed
EP-2678346-B9 METAL COMPLEXES FOR USE AS DOPANTS AND OTHER USES ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2018-08-08 EP disclosed
US-10038150-B2 Metal complexes for use as dopants and other uses ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2018-07-31 US disclosed
EP-2678346-B1 METAL COMPLEXES FOR USE AS DOPANTS AND OTHER USES ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2018-04-04 EP disclosed
EP-2253030-B1 ORGANIC SENSITIZERS ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2017-09-13 EP disclosed
US-9559321-B2 Metal complexes for use as dopants and other uses ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2017-01-31 US disclosed
US-20160233439-A1 METAL COMPLEXES FOR USE AS DOPANTS AND OTHER USES ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) EPFL-TTO (CH) 2016-08-11 US disclosed
US-20130330632-A1 METAL COMPLEXES FOR USE AS DOPANTS AND OTHER USES ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2013-12-12 US disclosed
US-8487119-B2 Organic sensitizers ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2013-07-16 US disclosed
US-8105865-B2 Liquid charge transporting material Ecole polytechnique fédérale de Lausanne (EPFL) (CH) 2012-01-31 US disclosed
EP-2325913-A1 A method for preparing a solar cell Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) 2011-05-25 EP disclosed
US-20110041907-A1 ORGANIC SENSITIZERS ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2011-02-24 US disclosed
US-20100051908-A1 Liquid Charge Transporting Material ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2010-03-04 US disclosed
US-20100051908-A1 Liquid Charge Transporting Material ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2010-03-04 US disclosed
US-20100051908-A1 Liquid Charge Transporting Material ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2010-03-04 US disclosed
EP-1994575-A1 LIQUID CHARGE TRANSPORTING MATERIAL Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) 2008-11-26 EP disclosed
WO-2007107961-A1 LIQUID CHARGE TRANSPORTING MATERIAL ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2007-09-27 WO disclosed
WO-2007107961-A1 LIQUID CHARGE TRANSPORTING MATERIAL ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2007-09-27 WO disclosed
EP-1837929-A1 Liquid Charge Transporting Material Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) 2007-09-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10038150-B2 Metal complexes for use as dopants and other uses SOD1, DDT, SOD3 KDM4E 4298/4885RECQL 1637/4885ALDH1A1 3311/4885
US-20160233439-A1 METAL COMPLEXES FOR USE AS DOPANTS AND OTHER USES SOD1, DDT, SOD3 KDM4E 4298/4885RECQL 1637/4885ALDH1A1 3311/4885
US-20100051908-A1 Liquid Charge Transporting Material SLCO4C1, SLC43A1, SLC6A19 KDM4E 3854/4885RECQL 1166/4885ALDH1A1 2432/4885
US-20110041907-A1 ORGANIC SENSITIZERS SLCO4C1, SLC16A3, EPCAM KDM4E 2150/4885RECQL 789/4885ALDH1A1 1305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.