SCHEMBL548276

SCHEMBL548276

CC(C)(O)c1ccc(O)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 12/20 0.65
ESR2 Q92731 11/20 0.65
CYP3A4 P08684 4/20 0.65
LMNA P02545 2/20 0.65
TYR P14679 2/20 0.65
HPGD P15428 2/20 0.65
HSD17B10 Q99714 2/20 0.65
AR P10275 1/20 0.65
TSHR P16473 1/20 0.65
SLC6A2 P23975 1/20 0.65
SLC6A4 P31645 1/20 0.65
HTR6 P50406 1/20 0.65
ESRRG P62508 1/20 0.65
SLC6A3 Q01959 1/20 0.65
ALDH1A1 P00352 3/20 0.54
SHBG P04278 1/20 0.52
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10781469 0.92 ESR1 (0.56) ESR1ESR2CYP3A4LMNATYR
SCHEMBL19792143 0.92 ESR1 (0.80) ESR1ESR2CYP3A4LMNATYR
SCHEMBL196799 0.87 MEN1 (0.48) ESR1ESR2CYP3A4LMNATYR
SCHEMBL20673138 0.82 ESR1 (0.65) ESR1ESR2CYP3A4LMNATYR
SCHEMBL6036607 0.82 ESR1 (0.65) ESR1ESR2CYP3A4LMNATYR
SCHEMBL13917765 0.82 ESR1 (0.65) ESR1ESR2CYP3A4LMNATYR
Phenol SCHEMBL10440204 0.81 ESR2 (0.60) ESR1ESR2CYP3A4LMNATYR
SCHEMBL18802754 0.79 KIF11 (0.44) ESR1ESR2CYP3A4LMNATYR
Bisphenol A SCHEMBL15062 0.79 ESR1 (1.00) ESR1ESR2CYP3A4LMNATYR
Bisphenol A SCHEMBL9774987 0.79 ESR1 (1.00) ESR1ESR2CYP3A4LMNATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114381484-B Application of UGT85A1 or RrUGT3 in catalyzing various substrates to generate glycoside compounds 山东大学 2024-04-19 CN claimed
CN-114381484-A Application of UGT85A1 or RrUGT3 in catalyzing various substrates to generate glycoside compounds 山东大学 2022-04-22 CN claimed
EP-1109770-A1 A METHOD FOR PREPARING BISPHENOL A GENERAL ELECTRIC COMPANY (US) 2001-06-27 EP claimed
US-6197916-B1 Method for preparing bisphenol A GENERAL ELECTRIC COMPANY 2001-03-06 US claimed
WO-2000012455-A1 A METHOD FOR PREPARING BISPHENOL A GENERAL ELECTRIC COMPANY (US) 2000-03-09 WO claimed
US-5990362-A Method for preparing bisphenol A GENERAL ELECTRIC COMPANY (US) 1999-11-23 US claimed
EP-3704094-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-03-11 EP disclosed
CN-121571169-A Catalyst based on cobalt-molybdenum bimetallic sulfide heterostructure and preparation method and application thereof 齐鲁工业大学(山东省科学院) 2026-02-27 CN disclosed
US-12421193-B2 GPR52 modulators and methods of use NEUROCRINE BIOSCIENCES, INC. (US) 2025-09-23 US disclosed
CN-119859118-A Synthesis method of 4- (2-hydroxy-2-propyl) cumene hydroperoxide 中国石油化工股份有限公司 2025-04-22 CN disclosed
US-20250122188-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2025-04-17 US disclosed
US-20240166652-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY ABBVIE INC. 2024-05-23 US disclosed
EP-4356971-A2 MODULATORS OF THE INTEGRATED STRESS PATHWAY Calico Life Sciences LLC (US) 2024-04-24 EP disclosed
US-4307223-A CONTAINING PHENOLIC CONSTITUENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-12-22 US disclosed
US-4258219-A Process for producing hydroquinone MITSUI TOATSU CHEMICALS, INC. (JP) 1981-03-24 US disclosed
EP-0021848-A1 Process and apparatus for the preparation of phenols MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1981-01-07 EP disclosed
US-4237035-A FOR COATINGS, ADHESIVES, MOLDING MATERIALS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-12-02 US disclosed
US-4230890-A PRECIPITATION BY TREATING AN ORGANIC SOLUTION OF HYDROCARBON OXIDATES WITH AN ALKALI METAL HYDROXIDE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1980-10-28 US disclosed
US-4207264-A DISCOLORATION INHIBITION THE GOODYEAR TIRE & RUBBER COMPANY (US) 1980-06-10 US disclosed
US-4045499-A ACID CATALYSTS BAYER AKTIENGESELLSCHAFT (DT) 1977-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122188-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY ATF4, ATF1, DDIT3 ESR1 1100/4885ESR2 482/4885CYP3A4 3526/4885
US-20240166652-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY ATF4, ATF1, DDIT3 ESR1 1100/4885ESR2 482/4885CYP3A4 3526/4885
US-12421193-B2 GPR52 modulators and methods of use GPR52, GPR68, GPR35 ESR1 644/4885ESR2 219/4885CYP3A4 2659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.