SCHEMBL8943856

SCHEMBL8943856

COc1ccc(N(c2ccc(C)cc2)c2ccc(C#Cc3ccc(N(c4ccc(C)cc4)c4ccc(OC)cc4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.56
APP P05067 2/20 0.53
MCHR1 Q99705 2/20 0.46
KCNH2 Q12809 1/20 0.46
RELA Q04206 1/20 0.46
ADK P55263 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
LMNA P02545 3/20 0.40
GRM5 P41594 1/20 0.40
GAA P10253 1/20 0.40
TP53 P04637 1/20 0.40
ACACB O00763 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22954305 0.92 APP (0.61) ACHEAPPMCHR1KCNH2ADK
SCHEMBL8943690 0.92 APP (0.61) ACHEAPPMCHR1KCNH2ADK
SCHEMBL12545287 0.88 ACHE (0.71) ACHERELACA12CA1CA2
SCHEMBL172190 0.88 ACHE (0.71) ACHERELACA12CA1CA2
SCHEMBL19958553 0.88 ACHE (0.71) ACHERELACA12CA1CA2
SCHEMBL10065624 0.88 ACHE (0.71) ACHERELACA12CA1CA2
SCHEMBL10525794 0.88 ACHE (0.71) ACHEAPPMCHR1KCNH2RELA
SCHEMBL348291 0.88 ACHE (0.71) ACHERELACA12CA1CA2
SCHEMBL15957572 0.86 GRM5 (0.50) ACHEAPPKCNH2ADKCA12
SCHEMBL15957575 0.86 GRM5 (0.50) ACHEAPPKCNH2ADKCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed