SCHEMBL8943902

SCHEMBL8943902

COc1ccc(N2c3ccccc3Oc3ccccc32)cc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 2/20 0.50
SMPD1 P17405 1/20 0.46
MGLL Q99685 1/20 0.46
MAPT P10636 4/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
POLB P06746 1/20 0.44
ELANE P08246 1/20 0.44
ALDH1A1 P00352 2/20 0.43
HTT P42858 1/20 0.43
PGR P06401 1/20 0.43
NR1H3 Q13133 1/20 0.43
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29396961 1.00 P2RX4 (0.50) P2RX4SMPD1MGLLMAPTMEN1
SCHEMBL21843392 0.88 P2RX4 (0.51) P2RX4MAPTMEN1KMT2AALDH1A1
SCHEMBL29394319 0.87 AHR (0.42) P2RX4SMPD1MGLLMAPTMEN1
SCHEMBL28708555 0.87 AHR (0.42) P2RX4SMPD1MGLLMAPTMEN1
SCHEMBL13623272 0.85 CYP2A6 (0.49) P2RX4SMPD1MGLLMAPTMEN1
SCHEMBL18770800 0.85 MGLL (0.55) MGLLMAPTMEN1KMT2APOLB
SCHEMBL29879853 0.85 MGLL (0.55) MGLLMAPTMEN1KMT2APOLB
SCHEMBL6123819 0.84 P2RX4 (0.47) P2RX4MAPT
SCHEMBL23220372 0.84 KDR (0.43) P2RX4SMPD1MAPTALDH1A1MAPK1
SCHEMBL19317143 0.84 ESR1 (0.56) MAPTMEN1KMT2AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114133385-B Hole transport material with carbazole as core and thiophene or phenoxazine as end group, and synthesis method and application thereof 华南师范大学 2023-05-23 CN disclosed
CN-114133385-A Hole transport material with carbazole as core and phenothiazine or phenoxazine as end group, and synthesis method and application thereof 华南师范大学 2022-03-04 CN disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-7718278-B2 Anthrancene derivative compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-05-18 US disclosed
US-7718278-B2 Anthrancene derivative compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-05-18 US disclosed
US-20080122346-A1 ANTHRANCENE DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-05-29 US disclosed
US-20080122346-A1 ANTHRANCENE DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-05-29 US disclosed
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 P2RX4 4533/4885SMPD1 3970/4885MGLL 1758/4885
US-20080122346-A1 ANTHRANCENE DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME AR, CRY2, ANTXR2 P2RX4 3007/4885SMPD1 4207/4885MGLL 4027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.