SCHEMBL8943928

SCHEMBL8943928

COc1ccc(Nc2ccc(OCCOc3ccc(Nc4ccc(OC)cc4C)cc3Nc3ccc(OC)cc3C)c(Nc3ccc(OC)cc3C)c2)c(C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.56
ADRA2A P08913 1/20 0.47
ADRA2C P18825 1/20 0.47
ADRA1D P25100 1/20 0.47
ADRA1A P35348 1/20 0.47
ADRA1B P35368 1/20 0.47
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
LMNA P02545 3/20 0.42
MAPT P10636 2/20 0.42
POLB P06746 1/20 0.42
CNR2 P34972 1/20 0.41
MAPK14 Q16539 1/20 0.41
EGFR P00533 2/20 0.40
ERBB3 P21860 2/20 0.40
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
FGFR2 P21802 1/20 0.39
PIK3CA P42336 1/20 0.39
PRKDC P78527 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943581 0.84 MAPT (0.55) GAAMEN1KMT2ALMNAMAPT
SCHEMBL8944086 0.82 MAPT (0.49) GAAMEN1KMT2ALMNAMAPT
SCHEMBL8943901 0.80 EGFR (0.54) GAAMEN1KMT2AMAPTPOLB
SCHEMBL8944010 0.80 MAPT (0.53) GAAMEN1KMT2ALMNAMAPT
SCHEMBL25634740 0.78 GAA (0.80) GAAADRA2AADRA2CADRA1DADRA1A
SCHEMBL8944395 0.78 MAPT (0.52) GAAMEN1KMT2ALMNAMAPT
SCHEMBL8943933 0.77 GAA (0.51) GAAADRA2AADRA2CADRA1DADRA1A
SCHEMBL6999192 0.76 GAA (0.75) GAAADRA2AADRA2CADRA1DADRA1A
SCHEMBL2952972 0.76 GAA (0.75) GAAADRA2AADRA2CADRA1DADRA1A
SCHEMBL8944279 0.75 MAPT (0.55) GAAMEN1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed