SCHEMBL8943901

SCHEMBL8943901

COc1cccc(Nc2ccc(OCCOc3ccc(Nc4cccc(OC)c4)cc3Nc3cccc(OC)c3)c(Nc3cccc(OC)c3)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 4/20 0.54
ERBB3 P21860 2/20 0.54
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 1/20 0.52
MTNR1B P49286 5/20 0.50
MTNR1A P48039 3/20 0.50
MAPK1 P28482 2/20 0.49
MAPT P10636 1/20 0.49
POLB P06746 1/20 0.49
AKR1C3 P42330 2/20 0.48
AKR1C2 P52895 2/20 0.48
KDR P35968 2/20 0.47
GAA P10253 1/20 0.47
GFER P55789 1/20 0.47
RET P07949 1/20 0.47
SRC P12931 1/20 0.47
RAPGEF4 Q8WZA2 1/20 0.47
DYRK3 O43781 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943581 0.86 MAPT (0.55) EGFRERBB3MEN1KMT2ANPC1
SCHEMBL8943909 0.82 MEN1 (0.56) EGFRERBB3MEN1KMT2ANPC1
SCHEMBL8943948 0.82 NPSR1 (0.51) EGFRMEN1KMT2AMAPK1MAPT
SCHEMBL8944010 0.82 MAPT (0.53) EGFRERBB3MEN1KMT2ANPC1
SCHEMBL8944086 0.81 MAPT (0.49) MEN1KMT2ANPC1RAB9AMAPK1
SCHEMBL8944395 0.81 MAPT (0.52) EGFRERBB3MEN1KMT2ANPC1
SCHEMBL8943983 0.80 ALDH1A1 (0.44) EGFRERBB3MEN1KMT2ANPC1
SCHEMBL8943928 0.80 GAA (0.56) EGFRERBB3MEN1KMT2ANPC1
SCHEMBL1921496 0.79 MTNR1B (0.72) EGFRMEN1KMT2ANPC1RAB9A
SCHEMBL1085867 0.79 MEN1 (0.71) EGFRERBB3MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed