SCHEMBL8943933

SCHEMBL8943933

COc1ccc(Nc2cccc(OCCOc3cccc(Nc4ccc(OC)cc4C)c3Nc3ccc(OC)cc3C)c2Nc2ccc(OC)cc2C)c(C)c1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.51
ADRA2A P08913 1/20 0.46
ADRA2C P18825 1/20 0.46
ADRA1D P25100 1/20 0.46
ADRA1A P35348 1/20 0.46
ADRA1B P35368 1/20 0.46
MAPK1 P28482 1/20 0.41
PIK3CA P42336 1/20 0.41
PRKDC P78527 1/20 0.41
P2RX7 Q99572 2/20 0.41
RAPGEF4 Q8WZA2 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
PTPN11 Q06124 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943909 0.79 MEN1 (0.56) GAAMAPK1RAPGEF4RAB9ANPSR1
SCHEMBL8769308 0.78 GAA (0.65) GAAADRA2AADRA2CADRA1DADRA1A
SCHEMBL8943587 0.77 ALDH1A1 (0.53) GAAMAPK1RAB9ANPSR1
SCHEMBL8943928 0.77 GAA (0.56) GAAADRA2AADRA2CADRA1DADRA1A
SCHEMBL10639862 0.76 GAA (0.72) GAAADRA2AADRA2CADRA1DADRA1A
SCHEMBL8943993 0.76 ALDH1A1 (0.51) GAAMAPK1RAPGEF4RAB9ANPSR1
SCHEMBL10640051 0.75 GAA (0.61) GAAADRA2AADRA2CADRA1DADRA1A
SCHEMBL8943887 0.73 ALDH1A1 (0.51) GAAMAPK1RAB9ANPSR1
SCHEMBL11228831 0.73 GAA (0.62) GAAADRA2AADRA2CADRA1DADRA1A
SCHEMBL8944399 0.72 ALDH1A1 (0.50) GAAMAPK1RAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed