Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943773 | 0.84 | MAPT (0.45) | SIRT2MAPTRAPGEF4KMT2AMEN1 | |
| SCHEMBL8943909 | 0.84 | MEN1 (0.56) | NPSR1MAPTHTTRAPGEF4KMT2A | |
| SCHEMBL8944280 | 0.80 | MAPT (0.44) | SIRT2MAPTRAPGEF4KMT2AMEN1 | |
| SCHEMBL8943948 | 0.80 | NPSR1 (0.51) | NPSR1SIRT2MAPTCYP1A2CYP3A4 | |
| SCHEMBL8943654 | 0.79 | MAPT (0.39) | NPSR1SIRT2MAPTCYP1A2CYP3A4 | |
| SCHEMBL8943993 | 0.77 | ALDH1A1 (0.51) | NPSR1MAPTHTTRAPGEF4KMT2A | |
| SCHEMBL8944257 | 0.77 | ALDH1A1 (0.40) | SIRT2MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8943983 | 0.76 | ALDH1A1 (0.44) | NPSR1SIRT2MAPTHTTRAPGEF4 | |
| SCHEMBL8943587 | 0.76 | ALDH1A1 (0.53) | NPSR1MAPTHTTKMT2AMEN1 | |
| SCHEMBL1922073 | 0.74 | NPSR1 (0.72) | NPSR1MAPTCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480765-A | PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |