SCHEMBL8943909

SCHEMBL8943909

COc1cccc(Nc2cccc(OCCOc3cccc(Nc4cccc(OC)c4)c3Nc3cccc(OC)c3)c2Nc2cccc(OC)c2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
POLB P06746 1/20 0.56
RAPGEF4 Q8WZA2 1/20 0.54
MAPK1 P28482 2/20 0.49
MAPT P10636 1/20 0.49
EGFR P00533 3/20 0.48
ERBB3 P21860 2/20 0.48
AKR1C3 P42330 1/20 0.48
AKR1C2 P52895 1/20 0.48
NPC1 O15118 2/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TSHR P16473 3/20 0.45
GFER P55789 2/20 0.45
IDO1 P14902 1/20 0.45
HTT P42858 1/20 0.45
GAA P10253 1/20 0.44
RET P07949 1/20 0.44
SRC P12931 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943587 0.87 ALDH1A1 (0.53) MEN1KMT2APOLBMAPK1MAPT
SCHEMBL8943955 0.84 NPSR1 (0.46) MEN1KMT2ARAPGEF4MAPTEGFR
SCHEMBL8943887 0.82 ALDH1A1 (0.51) MEN1KMT2APOLBMAPK1MAPT
SCHEMBL8943901 0.82 EGFR (0.54) MEN1KMT2APOLBRAPGEF4MAPK1
SCHEMBL8943993 0.82 ALDH1A1 (0.51) MEN1KMT2APOLBRAPGEF4MAPK1
SCHEMBL8944399 0.81 ALDH1A1 (0.50) MEN1KMT2APOLBMAPK1MAPT
SCHEMBL8943983 0.80 ALDH1A1 (0.44) MEN1KMT2APOLBRAPGEF4MAPK1
SCHEMBL8943933 0.79 GAA (0.51) RAPGEF4MAPK1RAB9ANPSR1GAA
SCHEMBL1921497 0.79 MEN1 (0.62) MEN1KMT2APOLBRAPGEF4MAPK1
SCHEMBL8944257 0.78 ALDH1A1 (0.40) MEN1KMT2AMAPK1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed