Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MARK3 | P27448 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 2/20 | 0.42 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.42 |
| ▸ | MARK2 | Q7KZI7 | 2/20 | 0.42 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.42 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.42 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943773 | 0.95 | MAPT (0.45) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL8943993 | 0.87 | ALDH1A1 (0.51) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL8944054 | 0.85 | HTR1A (0.44) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL8943887 | 0.85 | ALDH1A1 (0.51) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL8943654 | 0.84 | MAPT (0.39) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL8944399 | 0.84 | ALDH1A1 (0.50) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL8943788 | 0.82 | SGMS2 (0.41) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL8943587 | 0.80 | ALDH1A1 (0.53) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL8943955 | 0.80 | NPSR1 (0.46) | MAPTRAPGEF4SIRT2MEN1KMT2A | |
| SCHEMBL8943983 | 0.80 | ALDH1A1 (0.44) | MAPTGAATDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480765-A | PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |