SCHEMBL8944005

SCHEMBL8944005

COc1cc(N(c2ccccc2)c2ccccc2)c(OC)c(OC)c1OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 2/20 0.43
TUBB P07437 2/20 0.43
TUBA3C P0DPH7 2/20 0.43
TUBA1B P68363 2/20 0.43
TUBA4A P68366 2/20 0.43
TUBB4B P68371 2/20 0.43
TUBB3 Q13509 2/20 0.43
TUBB2A Q13885 2/20 0.43
TUBB8 Q3ZCM7 2/20 0.43
TUBA3E Q6PEY2 2/20 0.43
TUBA1A Q71U36 2/20 0.43
TUBA1C Q9BQE3 2/20 0.43
TUBB6 Q9BUF5 2/20 0.43
TUBB2B Q9BVA1 2/20 0.43
TUBB1 Q9H4B7 2/20 0.43
MAPT P10636 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6751444 0.85 TUBB4A (0.37) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL8943743 0.84 SMN1; SMN2 (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL30143822 0.84 SMN1; SMN2 (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL10065622 0.83 CA12 (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL31418752 0.82 ACHE (0.46) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL8944290 0.79 TUBB4A (0.52) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL8943991 0.79 TUBB4A (0.52) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL13053152 0.78 ACHE (0.39) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29589190 0.76 TRPM8 (0.46) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL13053120 0.76 KDM4E (0.35) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108976239-B Preparation method and application of organic hole transport material taking phthalocyanine as core 合肥工业大学 2020-11-17 CN disclosed
CN-108976239-A It is a kind of using phthalocyanine as the preparation method and applications of the organic hole transport material of core 合肥工业大学 2018-12-11 CN disclosed
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed