SCHEMBL8944016

SCHEMBL8944016

CCN(CC)c1ccc(C2(c3ccc(N(CC)CC)cc3C)OC(=O)c3nccnc32)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.38
ALDH1A1 P00352 6/20 0.38
HSD17B10 Q99714 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
CASP1 P29466 2/20 0.38
CASP7 P55210 2/20 0.38
GLA P06280 2/20 0.38
MAPK1 P28482 2/20 0.38
IGLV6-57 P01721 1/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
ATM Q13315 1/20 0.38
HIF1A Q16665 1/20 0.38
MAPT P10636 7/20 0.36
HTT P42858 4/20 0.36
KDM4E B2RXH2 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ALOX15 P16050 2/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9182905 0.90 ALDH1A1 (0.46) S100BALDH1A1HSD17B10L3MBTL1CASP1
SCHEMBL9184148 0.87 MAPT (0.39) S100BALDH1A1HSD17B10L3MBTL1CASP1
SCHEMBL8819033 0.86 CYP3A4 (0.35) ALDH1A1HSD17B10L3MBTL1CASP1CASP7
SCHEMBL9185746 0.86 ALDH1A1 (0.41) ALDH1A1HSD17B10L3MBTL1CASP1CASP7
SCHEMBL9185734 0.84 MAPT (0.41) S100BALDH1A1HSD17B10L3MBTL1CASP1
SCHEMBL11233667 0.83 RPS6KA2 (0.37) S100BALDH1A1HSD17B10L3MBTL1CASP1
SCHEMBL9183497 0.83 ALDH1A1 (0.37) S100BALDH1A1HSD17B10L3MBTL1CASP1
SCHEMBL10934926 0.83 GSK3A (0.33) ALDH1A1HSD17B10L3MBTL1CASP1CASP7
SCHEMBL11237305 0.82 S100B (0.34) S100BALDH1A1HSD17B10L3MBTL1CASP1
SCHEMBL24386021 0.81 CYP3A4 (0.34) ALDH1A1HSD17B10L3MBTL1CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7097527-A None JP disclosed
US-20240016965-A1 ULTRAVIOLET-SENSING MEMBER AND ULTRAVIOLET-SENSING KIT FUJIFILM CORPORATION (JP) 2024-01-18 US disclosed
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed
JP-H0797527-A CRYSTAL OF 3,3-BIS(4-DIETHYLAMINO-2-METHYLPHENYL)-4,7-DIAZAPHTHALIDE AND RECORDING MATERIAL CONTAINING THE SAME CRYSTAL YAMAMOTO CHEM INC 1995-04-11 JP disclosed
US-5401699-A Thermosensitive elements with color developers, fluoran derivatives and azaphthalides KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016965-A1 ULTRAVIOLET-SENSING MEMBER AND ULTRAVIOLET-SENSING KIT KIT, SARS1, UNG S100B 2324/4885ALDH1A1 1641/4885HSD17B10 3235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.