SCHEMBL8944057

SCHEMBL8944057

Cc1ccc(Nc2cccc(Oc3ccc(-c4ccc(Oc5cccc(Nc6ccc(C)cc6)c5Nc5ccc(C)cc5)cc4)cc3)c2Nc2ccc(C)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 3/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
HTR2A P28223 2/20 0.39
SLC6A4 P31645 2/20 0.39
ACP1 P24666 1/20 0.39
PKM P14618 1/20 0.38
PKLR P30613 1/20 0.38
RAPGEF4 Q8WZA2 1/20 0.38
HPGD P15428 1/20 0.37
KDM4E B2RXH2 1/20 0.37
POLB P06746 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
LMNA P02545 1/20 0.36
KCNH2 Q12809 2/20 0.36
SCN5A Q14524 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943655 0.95 MAPT (0.45) GAAMAPTTDP1ALDH1A1RAB9A
SCHEMBL8944203 0.94 GAA (0.44) GAAMAPTTDP1ALDH1A1RAB9A
SCHEMBL8943619 0.88 ALDH1A1 (0.51) GAAMAPTTDP1ALDH1A1RAB9A
SCHEMBL8943837 0.87 GAA (0.42) GAAMAPTTDP1ALDH1A1RAB9A
SCHEMBL8943622 0.83 ALDH1A1 (0.56) GAAMAPTTDP1ALDH1A1RAB9A
SCHEMBL8944040 0.82 ALDH1A1 (0.54) GAAMAPTTDP1ALDH1A1RAB9A
SCHEMBL23312022 0.79 MAPT (0.44) GAAMAPTTDP1ALDH1A1RAB9A
SCHEMBL8943773 0.77 MAPT (0.45) GAAMAPTTDP1ALDH1A1RAB9A
SCHEMBL8943962 0.77 ALDH1A1 (0.51) GAAMAPTTDP1ALDH1A1RAB9A
SCHEMBL8944306 0.76 LTA4H (0.50) RAB9ANPC1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed