Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943655 | 0.91 | MAPT (0.45) | GAAMAPTTDP1RAPGEF4NPC1 | |
| SCHEMBL8944203 | 0.89 | GAA (0.44) | GAAMAPTTDP1RAPGEF4NPC1 | |
| SCHEMBL8944057 | 0.87 | GAA (0.41) | GAAMAPTTDP1RAPGEF4NPC1 | |
| SCHEMBL8943962 | 0.87 | ALDH1A1 (0.51) | GAAMAPTTDP1RAPGEF4NPC1 | |
| SCHEMBL8943830 | 0.80 | HPGD (0.43) | GAAMAPTTDP1NPC1RAB9A | |
| SCHEMBL8943773 | 0.78 | MAPT (0.45) | GAAMAPTTDP1RAPGEF4NPC1 | |
| SCHEMBL8943622 | 0.78 | ALDH1A1 (0.56) | GAAMAPTTDP1NPC1RAB9A | |
| SCHEMBL8944040 | 0.77 | ALDH1A1 (0.54) | GAAMAPTTDP1NPC1RAB9A | |
| SCHEMBL8944280 | 0.77 | MAPT (0.44) | GAAMAPTTDP1RAPGEF4NPC1 | |
| SCHEMBL8943788 | 0.75 | SGMS2 (0.41) | GAAMAPTTDP1RAPGEF4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480765-A | PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |