Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16431886 | 0.82 | SMN1; SMN2 (0.54) | ALDH1A1HPGDNPC1MAPTKMT2A | |
| SCHEMBL27757036 | 0.81 | GAA (0.48) | ALDH1A1HPGDNPC1MAPTHTT | |
| SCHEMBL6670825 | 0.78 | KMT2A (0.50) | ALDH1A1NPC1MAPTHTTKMT2A | |
| SCHEMBL11290134 | 0.77 | CA1 (0.54) | ALDH1A1HPGDNPC1MAPTHTT | |
| SCHEMBL90967 | 0.77 | ALDH1A1 (0.59) | ALDH1A1HPGDNPC1KMT2AMEN1 | |
| SCHEMBL8716883 | 0.76 | KMT2A (0.65) | ALDH1A1HPGDNPC1MAPTHTT | |
| SCHEMBL8016782 | 0.76 | ALDH1A1 (0.57) | ALDH1A1HPGDNPC1MAPTHTT | |
| SCHEMBL31725340 | 0.76 | KMT2A (0.65) | ALDH1A1HPGDNPC1MAPTHTT | |
| SCHEMBL14668124 | 0.75 | TRPA1 (0.53) | ALDH1A1HPGDNPC1MAPTHTT | |
| SCHEMBL11310673 | 0.75 | HDAC3 (0.53) | ALDH1A1HPGDMAPTSMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543279-A | SMALL FLUCTUATION IN SENSITIVITY WITH TEMPERATURE CHANGE | FUJI PHOTO FILM CO., LTD. (JP) | 1996-08-06 | — | — | US | disclosed |