SCHEMBL6670825

SCHEMBL6670825

COc1ccc([C]=O)cc1NC(C)=O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 7/20 0.50
▸ MEN1 O00255 6/20 0.50
▸ ALDH1A1 P00352 8/20 0.48
▸ MAPT P10636 4/20 0.48
▸ GAA P10253 3/20 0.48
▸ KDM4E B2RXH2 2/20 0.48
▸ HTT P42858 2/20 0.48
▸ TSHR P16473 1/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ TP53 P04637 2/20 0.45
▸ NPC1 O15118 1/20 0.45
▸ LMNA P02545 1/20 0.45
▸ RAB9A P51151 1/20 0.45
▸ CHEK1 O14757 1/20 0.44
▸ HSD17B1 P14061 1/20 0.43
▸ HSD17B2 P37059 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29033307 0.86 ALDH1A1 (0.56) KMT2AMEN1ALDH1A1MAPTGAA
SCHEMBL30474632 0.86 ALDH1A1 (0.56) KMT2AMEN1ALDH1A1MAPTGAA
SCHEMBL29451289 0.78 SMN1; SMN2 (0.66) KMT2AMEN1ALDH1A1MAPTGAA
SCHEMBL16431886 0.78 SMN1; SMN2 (0.54) KMT2AMEN1ALDH1A1MAPTGAA
SCHEMBL10534559 0.78 PYGL (0.57) KMT2AMEN1ALDH1A1MAPTGAA
SCHEMBL6579496 0.78 SMN1; SMN2 (0.66) KMT2AMEN1ALDH1A1MAPTGAA
SCHEMBL8944090 0.78 ALDH1A1 (0.52) KMT2AMEN1ALDH1A1MAPTGAA
SCHEMBL2088259 0.78 ALDH1A1 (0.64) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL2502603 0.78 MAPT (0.71) KMT2AMEN1ALDH1A1MAPTGAA
Guanidine SCHEMBL10611817 0.78 KMT2A (0.45) KMT2AMEN1ALDH1A1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0772087-B1 Pyrazolylazophenol dye FUJI PHOTO FILM CO LTD (JP) 2004-09-08 — — EP disclosed
US-6495304-B2 NOVEL COLOR-DEVELOPING AGENT OF A 1,2,4- THIADIAZOL-5-YL HYDRAZINE TYPE FUJI PHOTO FILM CO., LTD. (JP) 2002-12-17 — — US disclosed
US-20020102489-A1 Color-developing agent, silver halide photographic light-sensitive material and image-forming method FUJIFILM CORPORATION (JP) 2002-08-01 — — US disclosed
EP-0903633-B1 Heat-developable color light-sensitive material FUJI PHOTO FILM CO LTD (JP) 2002-07-24 — — EP disclosed
US-6352821-B1 DEVELOPING SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL, SUPPLYING ACIDIC SOLUTION HAVING PH OF 4 OR LESS, IN FORM OF THIN LAYER, ONTO LIGHT-SENSITIVE MATERIAL, SO AS TO HAVE SPECIFIED COVERAGE FUJI PHOTO FILM CO., LTD. (JP) 2002-03-05 — — US disclosed
EP-0715209-B1 Heat-developable color light-sensitive material FUJI PHOTO FILM CO LTD (JP) 2002-02-13 — — EP disclosed
US-6277994-B1 IMAGE QUALITY AND IMAGE STORABILITY FUJI PHOTO FILM CO., LTD. (JP) 2001-08-21 — — US disclosed
US-6127088-A IMAGE-FORMING PROCESS COMPRISING HEATING HEAT DEVELOPABLE COLOR LIGHT-SENSITIVE MATERIAL WITH OR AFTER IMAGEWISE EXPOSURE, SAID MATERIAL COMPRISING SUPPORT BEARING SILVER HALIDE EMULSION LAYER AND CONTAINING SPECIFIED DYE PRECURSOR FUJI PHOTO FILM CO., LTD. (JP) 2000-10-03 — — US disclosed
US-6124084-A AZO DYES; GOOD FASTNESS TO COLOR, HUMIDITY AND HEAT FUJI PHOTO FILM CO., LTD. (JP) 2000-09-26 — — US disclosed
EP-0620491-B1 Heat developable color light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1999-12-15 — — EP disclosed
US-4994363-A Silver halide light-sensitive material containing a compound releasing a photographically useful group FUJI PHOTO FILM CO., LTD. (JP) 1991-02-19 — — US disclosed
US-4968598-A POSITIVE COLOR IMAGE BY DIFFUSION TRANSFER FUJI PHOTO FILM CO., LTD. (JP) 1990-11-06 — — US disclosed
US-H830-H CONTAINING A DESILVERING ACCELERATOR RELEASING COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-10-02 — — US disclosed
US-4956263-A BLACKAND WHITE PHOTOGRAPHIC FILM CONTAINING CONTAINING A HYDRAZINE DERIVATIVE; HIGH CONTRAST; DAYLIGHT USE; ANTISOILANTS; SAFELIGHT SAFETY FUJI PHOTO FILM CO., LTD. (JP) 1990-09-11 — — US disclosed
US-H817-H Photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-09-04 — — US disclosed
US-4942114-A FLUORESCENT, REFLECTIVE FUJI PHOTO FILM CO., LTD. (JP) 1990-07-17 — — US disclosed
US-4921785-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-05-01 — — US disclosed
EP-0334362-A2 Heat developable color light-sensitive material Fuji Photo Film Co., Ltd. (JP) 1989-09-27 — — EP disclosed
US-4840887-A USEFUL GROUP RELEASED BY CLEAVAGE BETWEEN SULFONYL GROUP AND A NITROGEN, SULFUR OR OXYGEN ATOM; STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1989-06-20 — — US disclosed
EP-0306833-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-03-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020102489-A1 Color-developing agent, silver halide photographic light-sensitive material and image-forming method SHH, GLI1, HELZ KMT2A 579/4885MEN1 2250/4885ALDH1A1 42/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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