Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 8/20 | 0.62 |
| ▸ | AGTR2 | P50052 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9590363 | 0.77 | AGTR1 (0.68) | AGTR1AGTR2MAPTEGFRERBB2 | |
| SCHEMBL6607228 | 0.77 | AGTR1 (0.61) | AGTR1AGTR2MAPTEGFRERBB2 | |
| SCHEMBL9592562 | 0.76 | AGTR1 (0.74) | AGTR1AGTR2MAPTEGFRERBB2 | |
| SCHEMBL18070888 | 0.74 | AGTR1 (0.61) | AGTR1AGTR2MAPTEGFRERBB2 | |
| SCHEMBL9589254 | 0.73 | AGTR1 (0.64) | AGTR1AGTR2MAPTEGFRERBB2 | |
| SCHEMBL8553594 | 0.71 | AGTR1 (0.44) | AGTR1AGTR2MAPTEGFRERBB2 | |
| SCHEMBL9593298 | 0.70 | AGTR1 (0.75) | AGTR1AGTR2MAPTALDH1A1HSD17B10 | |
| SCHEMBL6606668 | 0.69 | KDM4E (0.55) | AGTR1AGTR2MAPTEGFRERBB2 | |
| SCHEMBL6609133 | 0.68 | AGTR1 (0.58) | AGTR1AGTR2ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL9592095 | 0.67 | AGTR1 (0.69) | AGTR1AGTR2MAPTBDKRB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500427-A | ANGIOTENSIN II ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-19 | — | — | US | disclosed |