SCHEMBL8944128

SCHEMBL8944128

CCc1ccc(N(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 1/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
AOC3 Q16853 2/20 0.47
AGXT P21549 2/20 0.47
LTA4H P09960 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
ALDH1A1 P00352 2/20 0.45
ALOX15 P16050 2/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
TSHR P16473 1/20 0.45
ALOX12 P18054 1/20 0.45
APLNR P35414 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10062457 1.00 IDO1 (0.50) IDO1SMN1; SMN2LMNACA12CA1
SCHEMBL11888369 0.94 TAAR1 (0.52) IDO1SMN1; SMN2LMNAAOC3TAAR1
SCHEMBL12533874 0.94 MAOB (0.52) IDO1SMN1; SMN2LMNACA12CA1
SCHEMBL18674330 0.94 MAOB (0.52) IDO1SMN1; SMN2LMNACA12CA1
SCHEMBL13777812 0.92 LTA4H (0.55) IDO1SMN1; SMN2LMNALTA4HTP53
SCHEMBL14769812 0.91 LMNA (0.46) IDO1SMN1; SMN2LMNACA12CA1
SCHEMBL12514818 0.91 MEN1 (0.51) IDO1SMN1; SMN2LMNAAOC3AGXT
SCHEMBL13622954 0.89 TUBB1 (0.53) SMN1; SMN2LMNAALDH1A1TP53CYP3A4
SCHEMBL30878 0.89 CA12 (0.61) IDO1SMN1; SMN2LMNACA12CA1
SCHEMBL11887116 0.88 MAPT (0.51) LMNAAOC3TAAR1ALDH1A1CALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160225998-A1 CHARGE-TRANSPORTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-08-04 US disclosed
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed