SCHEMBL14769812

SCHEMBL14769812

CCc1ccc(N(c2ccc(CO)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
IDO1 P14902 2/20 0.42
AOC3 Q16853 2/20 0.41
CALM1 P0DP23 1/20 0.41
LTA4H P09960 2/20 0.40
NR1I2 O75469 1/20 0.40
AGXT P21549 1/20 0.40
MAPT P10636 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
HTT P42858 1/20 0.40
ALDH1A1 P00352 1/20 0.40
PKM P14618 1/20 0.40
LDHA P00338 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3929503 0.94 IDO1 (0.47) SMN1; SMN2IDO1AOC3CALM1LTA4H
SCHEMBL10062238 0.94 IDO1 (0.47) SMN1; SMN2IDO1AOC3CALM1LTA4H
SCHEMBL12732320 0.94 IDO1 (0.47) SMN1; SMN2IDO1AOC3CALM1LTA4H
SCHEMBL10062457 0.91 IDO1 (0.50) LMNASMN1; SMN2IDO1AOC3CALM1
SCHEMBL8944128 0.91 IDO1 (0.50) LMNASMN1; SMN2IDO1AOC3CALM1
SCHEMBL13777915 0.89 LMNA (0.40) LMNASMN1; SMN2IDO1AOC3MAPT
SCHEMBL12200966 0.89 MAOB (0.49) SMN1; SMN2IDO1AOC3CALM1NR1I2
SCHEMBL9892953 0.89 LTA4H (0.53) LMNASMN1; SMN2IDO1AOC3CALM1
SCHEMBL10065946 0.89 IDO1 (0.42) IDO1AOC3CALM1LTA4HNR1I2
SCHEMBL12611356 0.89 MAOB (0.49) SMN1; SMN2IDO1AOC3CALM1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703373-B2 Electrophotographic photoreceptor, method of producing electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2014-04-22 US disclosed
US-8703373-B2 Electrophotographic photoreceptor, method of producing electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2014-04-22 US disclosed
US-20130065169-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2013-03-14 US disclosed
US-20130065169-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2013-03-14 US disclosed