Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262478 | 0.79 | ESR1 (0.59) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL9781895 | 0.79 | CPN1 (0.47) | TSHRLMNAKDM4EGAACA12 | |
| SCHEMBL3496129 | 0.79 | ESR1 (0.59) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL9256909 | 0.79 | ESR1 (0.59) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL6966592 | 0.79 | ADRB1 (0.48) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL910504 | 0.78 | ADRB1 (0.52) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL8943834 | 0.78 | IDO1 (0.41) | SLC6A3ALDH1A1CYP3A4CA14CA1 | |
| SCHEMBL10482997 | 0.78 | ESR1 (0.44) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL10616896 | 0.78 | ACP3 (0.47) | ADRB1TSHRADRB2ADRB3LMNA | |
| SCHEMBL7192759 | 0.78 | ADRB1 (0.52) | ADRB1ADRA1AMIFHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532353-A | Process for the preparation of halogenated β-lactam compounds | BIOCHIMICA OPOS SPA (IT) | 1996-07-02 | — | — | US | disclosed |
| EP-0570058-A2 | Process for the preparation of halogenated beta-lactam compounds | BIOCHIMICA OPOS SPA (IT) | 1993-11-18 | — | — | EP | disclosed |
| EP-0211540-B1 | INTERMEDIATES AND PROCESS FOR ANTIBIOTICS | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1990-05-16 | — | — | EP | disclosed |
| EP-0244195-A1 | 2-Vinylpenams and process | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 1987-11-04 | — | — | EP | disclosed |
| US-4533497-A | N-ethylidene azetidinones | ELI LILLY AND COMPANY (US) | 1985-08-06 | — | — | US | disclosed |
| US-4281116-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4260745-A | 3-Halo cephalosporins | ELI LILLY AND COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4252950-A | ANTIBIOTICS, BACTERICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
| US-4208515-A | 3-Halo cephalosporins | ELI LILLY AND COMPANY (US) | 1980-06-17 | — | — | US | disclosed |
| US-4145538-A | 3-Carbamyloxymethyl-cephalosporins | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-4065618-A | Process for 3-H-3-cephem esters | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4064343-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-4060688-A | Cephalosporin intermediates | ELI LILLY AND COMPANY (US) | 1977-11-29 | — | — | US | disclosed |
| US-4013651-A | 3-SUBSTITUTED AMINO-CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-3992377-A | 3-Thio-substituted cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3988325-A | 7-Carboxy or 2,2,2-trichloroethoxy carbonyl- cephalosporins | ELI LILLY AND COMPANY (US) | 1976-10-26 | — | — | US | disclosed |
| US-3985737-A | ANTIBACTERIAL AGENTS | ELI LILLY AND COMPANY (US) | 1976-10-12 | — | — | US | disclosed |
| US-3962214-A | Process for preparing amino substituted β-lactam antibiotics | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3962227-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3954731-A | Process for preparing 6-alkoxypenicillanic and 7-alkoxycephalosporin acids | ELI LILLY AND COMPANY (US) | 1976-05-04 | — | — | US | disclosed |