Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 1.00 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944167 | 0.87 | CCR1 (0.75) | CCR1CCR5RAB9APDE10APARP1 | |
| SCHEMBL1579936 | 0.80 | CCR1 (0.65) | CCR1CCR5RAB9APDE10APARP1 | |
| SCHEMBL2707252 | 0.79 | CCR1 (0.63) | CCR1PDE10APARP1LMNAMAPT | |
| SCHEMBL6196701 | 0.79 | CCR1 (0.63) | CCR1RAB9APDE10APARP1KDM4E | |
| SCHEMBL201143 | 0.79 | CCR1 (0.63) | CCR1RAB9APDE10APARP1KDM4E | |
| SCHEMBL9684142 | 0.79 | CCR1 (0.63) | CCR1RAB9APDE10AKDM4ELMNA | |
| SCHEMBL4055648 | 0.74 | CCR1 (0.57) | CCR1PDE10APARP1KDM4EMAPT | |
| SCHEMBL4056183 | 0.74 | CCR1 (0.57) | CCR1RAB9APDE10AKDM4ELMNA | |
| SCHEMBL6088737 | 0.74 | CCR1 (0.57) | CCR1RAB9APDE10AKDM4EMAPT | |
| SCHEMBL8944497 | 0.73 | LMNA (0.61) | CCR1CCR5RAB9APDE10AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545639-A | USING 2,9-BIS(HALOMETHYL)-1,10-PHENANTHROLINE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-08-13 | — | — | US | claimed |
| EP-0180492-A1 | Macropolycyclic complexes of rare earth metals and application as fluorescent labels | CIS BIO INTERNATIONAL (FR) | 1986-05-07 | — | — | EP | claimed |
| US-8648064-B2 | Metal complexes of N-heterocyclic carbenes | THE UNIVERSITY OF AKRON (US) | 2014-02-11 | — | — | US | disclosed |
| US-8648064-B2 | Metal complexes of N-heterocyclic carbenes | THE UNIVERSITY OF AKRON (US) | 2014-02-11 | — | — | US | disclosed |
| US-8519146-B2 | Purine or imidazole and silver complexes; therapeutic, antimicrobial, and antifungal compounds; urinary tract infections | THE UNIVERSITY OF AKRON (US) | 2013-08-27 | — | — | US | disclosed |
| US-8519146-B2 | Purine or imidazole and silver complexes; therapeutic, antimicrobial, and antifungal compounds; urinary tract infections | THE UNIVERSITY OF AKRON (US) | 2013-08-27 | — | — | US | disclosed |
| US-20110086830-A1 | METAL COMPLEXES OF N-HETEROCYCLIC CARBENES | THE UNIVERSITY OF AKRON (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086830-A1 | METAL COMPLEXES OF N-HETEROCYCLIC CARBENES | THE UNIVERSITY OF AKRON (US) | 2011-04-14 | — | — | US | disclosed |
| US-RE42152-E1 | Aromatic-linked polyamine macrocyclic compounds with anti-HIV activity | GENZYME CORPORATION (US) | 2011-02-15 | — | — | US | disclosed |
| US-7696361-B2 | Chemical reagents capable of selective attachment to and reaction with peptides and proteins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2010-04-13 | — | — | US | disclosed |
| US-20080267867-A1 | Metal Complexes of N-Heterocyclic Carbenes as Radiopharmaceuticals and Antibiotics | UNIVERSITY OF AKRON | 2008-10-30 | — | — | US | disclosed |
| US-20050010059-A1 | Chemical reagents capable of selective attachment to and reaction with peptides and proteins | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2005-01-13 | — | — | US | disclosed |
| EP-1223166-A1 | Linked cyclic polyamines with activity against hiv. | AnorMED Inc. (CA) | 2002-07-17 | — | — | EP | disclosed |
| US-5583131-A | FOR TREATMENT OR PREVENTION OF ACQUIRED IMMUNE DEFICIENCY SYNDROME, REDUCED TOXICITY | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1996-12-10 | — | — | US | disclosed |
| US-5545639-A | USING 2,9-BIS(HALOMETHYL)-1,10-PHENANTHROLINE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-08-13 | — | — | US | disclosed |
| US-5262526-A | Fluorescent compound, complex, reagent, and specific binding assay employing said reagent | DOJINDO LABORATORIES (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0493745-A1 | Fluorescent compound, complex, reagent, and specific binding assay employing said reagent | DOJINDO LABORATORIES (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4859777-A | Terpyridine chelating agents | EASTMAN KODAK COMPANY (US) | 1989-08-22 | — | — | US | disclosed |
| US-4837169-A | RADIOIMMUNOASSAY | EASTMAN KODAK COMPANY (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0288256-A2 | Fluorescent labels | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267867-A1 | Metal Complexes of N-Heterocyclic Carbenes as Radiopharmaceuticals and Antibiotics | MKI67, C1S, CYC1 | CCR1 257/4885CCR5 988/4885RAB9A 2421/4885 |
| US-20050010059-A1 | Chemical reagents capable of selective attachment to and reaction with peptides and proteins | PTMS, FGB, DNPEP | CCR1 856/4885CCR5 1333/4885RAB9A 3665/4885 |
| US-20110086830-A1 | METAL COMPLEXES OF N-HETEROCYCLIC CARBENES | NOD2, ARNT, FPR1 | CCR1 115/4885CCR5 144/4885RAB9A 3565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.