SCHEMBL8944222

SCHEMBL8944222

COc1ccc(N(c2ccc(Sc3ccccc3)cc2)c2ccc(Sc3ccccc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.46
PTGIR P43119 7/20 0.46
LTA4H P09960 2/20 0.45
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
POLB P06746 1/20 0.43
MAPT P10636 3/20 0.43
ALDH1A1 P00352 2/20 0.42
HTR2C P28335 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP12 P39900 1/20 0.42
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TRPA1 O75762 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943939 0.98 CA4 (0.45) CA4PTGIRLTA4HMEN1KMT2A
SCHEMBL8943632 0.96 CA4 (0.46) CA4PTGIRLTA4HMEN1KMT2A
SCHEMBL8943944 0.92 PTGIR (0.52) PTGIRMEN1KMT2APOLBHTR2C
SCHEMBL2272158 0.88 CA4 (0.59) CA4PTGIRLTA4HMEN1KMT2A
SCHEMBL8944197 0.85 ACHE (0.56) PTGIRPOLBMAPTALDH1A1LMNA
SCHEMBL8944075 0.85 LTA4H (0.42) LTA4HMAPTALDH1A1LMNAHTT
SCHEMBL13720711 0.84 CA4 (0.59) CA4LTA4HKMT2AMAPTALDH1A1
SCHEMBL3339294 0.84 CA4 (0.59) CA4LTA4HKMT2AMAPTALDH1A1
SCHEMBL10065630 0.84 CA4 (0.59) CA4LTA4HKMT2AMAPTALDH1A1
SCHEMBL13720596 0.84 CA4 (0.59) CA4LTA4HKMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed