SCHEMBL2272158

SCHEMBL2272158

COc1ccc(Sc2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.59
LTA4H P09960 2/20 0.56
PTGIR P43119 3/20 0.55
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
TRPA1 O75762 1/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 4/20 0.49
ALDH1A1 P00352 3/20 0.49
HTR2C P28335 1/20 0.49
MMP2 P08253 1/20 0.49
MMP9 P14780 1/20 0.49
MMP12 P39900 1/20 0.49
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482369 0.90 CA1 (0.65) CA4PTGIRCA12CA1CA2
SCHEMBL29798085 0.89 MMP2 (0.56) CA4LTA4HPTGIRMEN1KMT2A
SCHEMBL1127975 0.88 CA4 (0.46) CA4LTA4HPTGIRCA12CA1
SCHEMBL8944222 0.88 CA4 (0.46) CA4LTA4HPTGIRCA12CA1
Hydrochloric Acid SCHEMBL11848856 0.87 CA1 (0.61) CA4PTGIRCA12CA1CA2
SCHEMBL8943939 0.87 CA4 (0.45) CA4LTA4HPTGIRMEN1KMT2A
SCHEMBL9018822 0.86 CA4 (0.59) CA4LTA4HCA12CA1CA2
SCHEMBL8577960 0.85 PTGIR (0.44) CA4LTA4HPTGIRCA12CA1
SCHEMBL6482376 0.85 ALDH1A1 (0.58) PTGIRCA1CA2MEN1KMT2A
SCHEMBL6136227 0.85 MMP2 (0.52) CA4LTA4HPTGIRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250339565-A1 METHOD FOR SYNTHESIZING IODO- OR ASTATOARYL COMPOUNDS USING ARYLSULFONIUM SALTS INST NAT SANTE RECH MED (FR) 2025-11-06 US disclosed
US-12032288-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, and method for manufacturing electronic device FUJIFILM CORPORATION (JP) 2024-07-09 US disclosed
WO-2023222909-A1 METHOD FOR SYNTHESIZING IODO- OR ASTATOARYL COMPOUNDS USING ARYLSULFONIUM SALTS Institut National de la Santé et de la Recherche Médicale (FR) 2023-11-23 WO disclosed
CN-116657163-A Method for dithioating o-dihalogenated aromatic hydrocarbon 河南大学 2023-08-29 CN disclosed
US-11427536-B2 Photocatalyst-free, light-induced carbon-sulfur cross-coupling methods THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2022-08-30 US disclosed
CN-111635343-B Preparation method of aryl monosulfide compound 武汉工程大学 2022-05-10 CN disclosed
WO-2021195176-A1 PROCESSES AND AGENTS FOR GLAUCOMA AUFBAU MEDICAL INNOVATIONS LIMITED (IE) 2021-09-30 WO disclosed
CN-110003065-B Method for synthesizing asymmetric sulfide by catalyzing molecular oxygen oxidation water phase with water-soluble transition metal complex 郑州大学 2021-01-05 CN disclosed
CN-111635343-A Preparation method of aryl monosulfide compound 武汉工程大学 2020-09-08 CN disclosed
US-20180370911-A1 PHOTOCATALYST-FREE, LIGHT-INDUCED CARBON-SULFUR CROSS-COUPLING METHODS U.S. DEPARTMENT OF ENERGY 2018-12-27 US disclosed
EP-1416301-A1 Material composition for producing optical-waveguide and method for producing optical waveguide Toyoda Gosei Co., Ltd. (JP) 2004-05-06 EP disclosed
EP-1294657-A2 CATALYSIS USING PHOSPHINE OXIDE AND SULFOXIDE COMPOUNDS E. I. du Pont de Nemours and Company (US) 2003-03-26 EP disclosed
US-20020137974-A1 Catalysis using phosphine oxide and sulfoxide compounds DUPONT POLYMERS, INC. 2002-09-26 US disclosed
WO-2002000574-A2 CATALYSIS USING PHOSPHINE OXIDE AND SULFOXIDE COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2002-01-03 WO disclosed
US-6136425-A SUITABLE FOR A PRINTING PLATE WHICH GIVES AN EXCELLENT WATER RETENTION PROPERTY AND PREVENTS STAINS FROM OCCURRING AT NON-IMAGE PORTIONS KONICA CORPORATION (JP) 2000-10-24 US disclosed
WO-1998039312-A1 STABLE ARENEDIAZONIUM SALTS, A PROCESS FOR THE PREPARATION THEREOF AND THE USES THEREOF CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1998-09-11 WO disclosed
US-4837301-A FROM ALKALI MTEAL SULFIDES AND AROMATIC DIHALOGEN COMPOUNDS; IMPROVED CORROSION RESISTANCE BAYER AKTIENGESELLSCHAFT (DE) 1989-06-06 US disclosed
EP-0275007-A2 Process for the preparation of highly molecular, optionally branched polyarylene sulfides BAYER AG (DE) 1988-07-20 EP disclosed
US-4251521-A HYPOGLYCEMIC AGENTS SANDOZ, INC. (US) 1981-02-17 US disclosed
US-4120866-A REACTING AN AROMATIC COMPOUND WITH A SULFOXIDE BAYER AKTIENGESELLSCHAFT (DE) 1978-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020137974-A1 Catalysis using phosphine oxide and sulfoxide compounds TST, GSS, ARSA CA4 4122/4885LTA4H 2659/4885PTGIR 2327/4885
US-20180370911-A1 PHOTOCATALYST-FREE, LIGHT-INDUCED CARBON-SULFUR CROSS-COUPLING METHODS TST, CBS, CRY2 CA4 688/4885LTA4H 1139/4885PTGIR 4107/4885
US-20250339565-A1 METHOD FOR SYNTHESIZING IODO- OR ASTATOARYL COMPOUNDS USING ARYLSULFONIUM SALTS ARSA, STS, AADAC CA4 3160/4885LTA4H 1226/4885PTGIR 3132/4885
US-11427536-B2 Photocatalyst-free, light-induced carbon-sulfur cross-coupling methods TST, CBS, CRY2 CA4 688/4885LTA4H 1139/4885PTGIR 4107/4885
US-12032288-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, and method for manufacturing electronic device RER1, COL1A1, RAD51 CA4 3661/4885LTA4H 812/4885PTGIR 3145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.