Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547975 | 0.79 | KDM4E (0.39) | KDM4ENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8550850 | 0.79 | KDM4E (0.39) | KDM4ENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8944237 | 0.71 | LTB4R2 (0.62) | LTB4R2AGTR1 | |
| SCHEMBL8550193 | 0.71 | MME (0.37) | AGTR1 | |
| SCHEMBL8880408 | 0.69 | BDKRB1 (0.47) | BDKRB1SLC6A3LTB4R2SLC6A4AGTR1 | |
| SCHEMBL8548947 | 0.68 | LTB4R2 (0.41) | KDM4ENPC1RAB9AKMT2ABDKRB1 | |
| SCHEMBL26503419 | 0.68 | NPC1 (0.62) | KDM4ENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8877960 | 0.67 | BDKRB1 (0.39) | BDKRB1SLC6A3LTB4R2SLC6A4AGTR1 | |
| SCHEMBL9088926 | 0.67 | BRS3 (0.38) | KDM4ERAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8876246 | 0.67 | BDKRB1 (0.40) | BDKRB1SLC6A3LTB4R2SLC6A4AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500427-A | ANGIOTENSIN II ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-19 | — | — | US | disclosed |