Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944270 | 1.00 | ACHE (0.42) | ACHEKMT2AGAARECQLMEN1 | |
| SCHEMBL16735694 | 0.71 | MAPK1 (0.33) | — | |
| SCHEMBL2344953 | 0.70 | — | — | |
| SCHEMBL22299280 | 0.69 | MAPK1 (0.32) | — | |
| SCHEMBL14276074 | 0.69 | KMT2A (0.39) | ACHEKMT2AGAARECQLMEN1 | |
| SCHEMBL2352775 | 0.67 | — | — | |
| SCHEMBL9353783 | 0.67 | PSEN1 (0.30) | KMT2A | |
| SCHEMBL9353778 | 0.67 | PSEN1 (0.30) | KMT2A | |
| SCHEMBL29752582 | 0.65 | ACHE (0.46) | ACHEKMT2AGAARECQLALDH1A1 | |
| SCHEMBL17791237 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514806-A | Method of preparing 1-amino-2, 6-dimethylpiperidine | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-05-07 | — | — | US | claimed |
| US-5510489-A | Method of preparing 1-amino-2, 6-dimethylpiperidine | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | claimed |
| EP-0613473-A1 | METHOD OF PREPARING 1-AMINO-2,6-DIMETHYLPIPERIDINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-07 | — | — | EP | claimed |
| EP-0613474-A1 | METHOD OF PREPARING 1-AMINO-2,6-DIMETHYLPIPERIDINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-07 | — | — | EP | claimed |
| WO-1993010109-A1 | METHOD OF PREPARING 1-AMINO-2,6-DIMETHYLPIPERIDINE | CASSELLA AKTIENGESELLSCHAFT (DE) | 1993-05-27 | — | — | WO | claimed |
| WO-1993010110-A1 | METHOD OF PREPARING 1-AMINO-2,6-DIMETHYLPIPERIDINE | CASSELLA AKTIENGESELLSCHAFT (DE) | 1993-05-27 | — | — | WO | claimed |
| US-5514806-A | Method of preparing 1-amino-2, 6-dimethylpiperidine | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-05-07 | — | — | US | disclosed |
| US-5510489-A | Method of preparing 1-amino-2, 6-dimethylpiperidine | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | disclosed |
| EP-0613474-A1 | METHOD OF PREPARING 1-AMINO-2,6-DIMETHYLPIPERIDINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-07 | — | — | EP | disclosed |
| EP-0613473-A1 | METHOD OF PREPARING 1-AMINO-2,6-DIMETHYLPIPERIDINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-07 | — | — | EP | disclosed |
| WO-1993010110-A1 | METHOD OF PREPARING 1-AMINO-2,6-DIMETHYLPIPERIDINE | CASSELLA AKTIENGESELLSCHAFT (DE) | 1993-05-27 | — | — | WO | disclosed |
| WO-1993010109-A1 | METHOD OF PREPARING 1-AMINO-2,6-DIMETHYLPIPERIDINE | CASSELLA AKTIENGESELLSCHAFT (DE) | 1993-05-27 | — | — | WO | disclosed |