SCHEMBL8944292

SCHEMBL8944292

Cc1ccccc1N(c1cccc(N(c2ccccc2C)c2ccccc2C)c1)c1ccccc1C

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ACHE P22303 1/20 0.39
ALDH1A1 P00352 5/20 0.35
CYP2A6 P11509 3/20 0.35
CYP1A2 P05177 2/20 0.35
SIGMAR1 Q99720 1/20 0.34
LMNA P02545 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CYP3A4 P08684 3/20 0.33
TRPM8 Q7Z2W7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29372483 0.91 ACHE (0.43) TSHRACHEALDH1A1CYP2A6CYP1A2
SCHEMBL312994 0.91 ACHE (0.43) TSHRACHEALDH1A1CYP2A6CYP1A2
SCHEMBL21173774 0.90 ACHE (0.42) ACHEALDH1A1CYP2A6CYP1A2SIGMAR1
SCHEMBL2505002 0.88 ALDH1A1 (0.53) TSHRACHEALDH1A1CYP1A2SIGMAR1
SCHEMBL15553940 0.86 ALDH1A1 (0.42) TSHRACHEALDH1A1LMNA
SCHEMBL29007292 0.86 CYP3A4 (0.39) ALDH1A1CYP1A2SIGMAR1LMNACYP3A4
SCHEMBL8470149 0.86 TSHR (0.43) TSHRACHEALDH1A1CYP1A2SIGMAR1
SCHEMBL13292332 0.84 TSHR (0.38) TSHRACHEALDH1A1CYP2A6CYP1A2
SCHEMBL3370034 0.84 TSHR (0.38) TSHRACHEALDH1A1CYP1A2SIGMAR1
SCHEMBL17032801 0.84 AR (0.33) TSHRCYP1A2CYP3A4TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5262260-A Photoreceptor containing carrier transport with polysilane and phenylene diamine TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) 1993-11-16 US claimed
JP-4013776-A None JP disclosed
US-9564599-B2 Organic electroluminescent device having specific diamine compound UDC IRELAND LIMITED (IE) 2017-02-07 US disclosed
US-9564599-B2 Organic electroluminescent device having specific diamine compound UDC IRELAND LIMITED (IE) 2017-02-07 US disclosed
US-20150243900-A1 Organic Electroluminescent Device Having Specific Diamine Compound UDC IRELAND LTD (IE) 2015-08-27 US disclosed
US-20150243900-A1 Organic Electroluminescent Device Having Specific Diamine Compound UDC IRELAND LTD (IE) 2015-08-27 US disclosed
US-8980441-B2 Organic electroluminescent device having specific diamine compound UDC IRELAND LIMITED (IE) 2015-03-17 US disclosed
US-8980441-B2 Organic electroluminescent device having specific diamine compound UDC IRELAND LIMITED (IE) 2015-03-17 US disclosed
US-20100155712-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-06-24 US disclosed
US-20100155712-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-06-24 US disclosed
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed
EP-0455247-B1 m-Phenylenediamine compound and electrophotosensitive material using said compound MITA INDUSTRIAL CO LTD (JP) 1995-09-13 EP disclosed
JP-H0413776-A M-PHENYSLNEDIAMINE COMPOUND AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR CONTAINING THE SAME MITA IND CO LTD 1992-01-17 JP disclosed
EP-0455247-A2 m-Phenylenediamine compound and electrophotosensitive material using said compound MITA INDUSTRIAL CO. LTD. (JP) 1991-11-06 EP disclosed