Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | BCR | P11274 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10160618 | 1.00 | KDM4E (0.50) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL13879190 | 1.00 | KDM4E (0.50) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL131837 | 0.98 | CA4 (0.52) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL15807457 | 0.98 | CA4 (0.52) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL10057794 | 0.98 | CA4 (0.52) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL10057799 | 0.98 | CA4 (0.52) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL16508421 | 0.98 | CA4 (0.52) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL6139896 | 0.98 | CA4 (0.52) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL13715237 | 0.98 | CA4 (0.52) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL12677664 | 0.98 | CA4 (0.52) | KDM4ENPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2278407-B1 | Image forming apparatus | RICOH CO LTD (JP) | 2012-10-10 | — | — | EP | disclosed |
| US-20090118521-A1 | NANOENGINEERED ORGANIC NONLINEAR OPTICAL GLASSES | WASHINGTON, UNIVERSITY OF (US) | 2009-05-07 | — | — | US | disclosed |
| US-5480765-A | PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| US-5227449-A | Polydiphenylsiloxane-Carbonate Block Polymers | XEROX CORPORATION (US) | 1993-07-13 | — | — | US | disclosed |
| US-5215844-A | Photoconductive imaging members with polyhydroxy ether binders | XEROX CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| US-5166021-A | Multilayer imaging member with charge generating and charge transport layers | XEROX CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5162485-A | Binders in charge transport or charge generation layers | XEROX CORPORATION (US) | 1992-11-10 | — | — | US | disclosed |
| US-5080987-A | Photoconductive imaging members with polycarbonate binders | XEROX CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
| US-5011906-A | Photoconductive imaging members with N,N-bis(biarylyl)aniline charge transport polymers | XEROX CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| US-5008169-A | Photoconductive imaging members with polyphosphazenes | XEROX CORPORATION (US) | 1991-04-16 | — | — | US | disclosed |
| US-5004663-A | Photoconductive imaging members with polyphosphazene binders | XEROX CORPORATION (US) | 1991-04-02 | — | — | US | disclosed |
| US-4959288-A | Photoconductive imaging members with diaryl biarylylamine copolymer charge transport layers | XEROX CORPORATION (US) | 1990-09-25 | — | — | US | disclosed |
| US-4946754-A | Photoconductive imaging members with diaryl biarylylamine charge transporting components | XEROX CORPORATION (US) | 1990-08-07 | — | — | US | disclosed |
| US-4937165-A | Photoconductive imaging members with N,N-bis(biarylyl)aniline charge transport polymers | XEROX CORPORATION (US) | 1990-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118521-A1 | NANOENGINEERED ORGANIC NONLINEAR OPTICAL GLASSES | EYA3, CDH1, EYA2 | KDM4E 1607/4885NPC1 1271/4885RAB9A 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.