Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 2/20 | 0.43 |
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH4 | P08319 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28684578 | 1.00 | ADH1A (0.43) | ADH1AADH1CADH4L3MBTL1MEN1 | |
| SCHEMBL28098320 | 0.91 | ADH1C (0.47) | ADH1AADH1CADH4DNM1TSHR | |
| SCHEMBL27868845 | 0.91 | ADH1C (0.47) | ADH1AADH1CADH4DNM1TSHR | |
| SCHEMBL28228737 | 0.80 | ADH1C (0.32) | ADH1AADH1CADH4SMN1; SMN2 | |
| SCHEMBL3710483 | 0.77 | ADH1A (0.38) | ADH1AADH1CSMN1; SMN2 | |
| SCHEMBL26160891 | 0.75 | DNM1 (0.41) | ADH1AADH1CADH4L3MBTL1MEN1 | |
| SCHEMBL1749630 | 0.74 | ADH1C (0.34) | ADH1AADH1CSMN1; SMN2 | |
| SCHEMBL3700583 | 0.73 | SMN1; SMN2 (0.39) | MEN1KMT2ATDP1SMN1; SMN2KDM4E | |
| SCHEMBL8894973 | 0.72 | DNM1 (0.42) | ADH1AADH1CADH4L3MBTL1MEN1 | |
| SCHEMBL28915967 | 0.72 | DNM1 (0.42) | ADH1AADH1CADH4L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |