SCHEMBL8944543

SCHEMBL8944543

CCCNCCC1CCCCCC1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.54
SIGMAR1 Q99720 3/20 0.45
EPHX1 P07099 2/20 0.40
BCHE P06276 3/20 0.40
CHRM2 P08172 3/20 0.39
CHRM1 P11229 3/20 0.39
CHRM3 P20309 3/20 0.39
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.36
ADH1B P00325 1/20 0.35
ADH1C P00326 1/20 0.35
ADH1A P07327 1/20 0.35
ADH4 P08319 1/20 0.35
ADH7 P40394 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KDM1A O60341 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4660951 1.00 CYP1A2 (0.54) CYP1A2SIGMAR1EPHX1BCHECHRM2
SCHEMBL7467108 0.98 CYP1A2 (0.50) CYP1A2SIGMAR1EPHX1BCHECHRM2
SCHEMBL24127642 0.93 CYP1A2 (0.44) CYP1A2SIGMAR1EPHX1BCHECHRM2
SCHEMBL5383682 0.88
SCHEMBL716430 0.88 SIGMAR1 (0.48) CYP1A2SIGMAR1EPHX1BCHECHRM2
SCHEMBL12288486 0.87 CYP1A2 (0.61) CYP1A2SIGMAR1EPHX1BCHEALDH1A1
SCHEMBL629782 0.87 CYP1A2 (0.61) CYP1A2SIGMAR1EPHX1BCHEALDH1A1
SCHEMBL8258527 0.87 CYP1A2 (0.61) CYP1A2SIGMAR1EPHX1BCHEALDH1A1
SCHEMBL8391404 0.87 CYP1A2 (0.61) CYP1A2SIGMAR1EPHX1BCHEALDH1A1
Hydrochloric Acid SCHEMBL5384906 0.86 SAT1 (0.40) CYP1A2SIGMAR1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3495363-B1 NITROGEN-CONTAINING CONDENSED RING COMPOUNDS HAVING DOPAMINE D3 RECEPTOR ANTAGONISTIC EFFECT SHIONOGI & CO (JP) 2023-08-23 EP disclosed
US-5541229-A ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS DR. KARL THOMAE GMBH (DE) 1996-07-30 US disclosed