Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349495 | 0.84 | GPR35 (0.41) | GPR35MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL22004332 | 0.84 | ACLY (0.47) | GPR35MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL17427791 | 0.83 | MEN1 (0.42) | MEN1KMT2AKDM4ETDP1NPC1 | |
| SCHEMBL862785 | 0.76 | ALDH1A1 (0.39) | MEN1KMT2AKDM4ETDP1NPC1 | |
| SCHEMBL5246480 | 0.74 | MEN1 (0.45) | MEN1KMT2AKDM4ETDP1DAO | |
| SCHEMBL4378545 | 0.74 | MEN1 (0.57) | MEN1KMT2AKDM4ETDP1NPC1 | |
| SCHEMBL21166602 | 0.73 | MEN1 (0.37) | MEN1KMT2AKDM4ETDP1NPC1 | |
| SCHEMBL11719401 | 0.73 | MEN1 (0.40) | MEN1KMT2AKDM4ETDP1NPC1 | |
| SCHEMBL18177589 | 0.71 | MEN1 (0.39) | MEN1KMT2AKDM4ETDP1NPC1 | |
| SCHEMBL11783996 | 0.71 | GPR35 (1.00) | GPR35KDM4EDAOHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1042393-C | Application of indole derivatives in dyeing of keratose fibre as colour | OREAL (FR) | 1999-03-10 | — | — | CN | claimed |
| EP-0496653-B1 | Use of indol derivatives as coupling agents in dyeing of keratin fibres | OREAL (FR) | 1995-09-13 | — | — | EP | claimed |
| CN-1063409-A | Indole derivatives is done the application of colour former in the dyeing keratinous fibres process | OREAL (FR) | 1992-08-12 | — | — | CN | claimed |
| EP-0496653-A1 | Use of indol derivatives as coupling agents in dyeing of keratin fibres | L'OREAL (FR) | 1992-07-29 | — | — | EP | claimed |
| CN-1042393-C | Application of indole derivatives in dyeing of keratose fibre as colour | OREAL (FR) | 1999-03-10 | — | — | CN | disclosed |
| US-5518505-A | Compositions and methods for the dyeing of keratinous fibers with oxidation dye precursors, indole derivative couplers and oxidizing agents | L'OREAL (FR) | 1996-05-21 | — | — | US | disclosed |
| EP-0496653-B1 | Use of indol derivatives as coupling agents in dyeing of keratin fibres | OREAL (FR) | 1995-09-13 | — | — | EP | disclosed |
| CN-1063409-A | Indole derivatives is done the application of colour former in the dyeing keratinous fibres process | OREAL (FR) | 1992-08-12 | — | — | CN | disclosed |
| EP-0496653-A1 | Use of indol derivatives as coupling agents in dyeing of keratin fibres | L'OREAL (FR) | 1992-07-29 | — | — | EP | disclosed |