Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | CASP6 | P55212 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.49 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31219526 | 0.85 | ALDH1A1 (0.59) | MAPTCASP6POLBAPEX1CTSB | |
| SCHEMBL17998719 | 0.85 | ALDH1A1 (0.59) | MAPTCASP6POLBAPEX1CTSB | |
| SCHEMBL9162298 | 0.84 | CTSB (0.59) | MAPTCASP6POLBAPEX1CTSB | |
| SCHEMBL8944627 | 0.81 | ALDH1A1 (0.59) | MAPTCASP6POLBAPEX1CTSB | |
| SCHEMBL27330819 | 0.79 | CTSB (0.53) | MAPTCASP6POLBAPEX1CTSB | |
| SCHEMBL19660346 | 0.79 | HPRT1 (0.61) | MAPTCASP6POLBAPEX1CTSB | |
| SCHEMBL24326903 | 0.79 | ALDH1A1 (0.51) | MAPTCASP6POLBAPEX1CTSB | |
| SCHEMBL20029707 | 0.79 | ALDH1A1 (0.51) | MAPTCASP6POLBAPEX1CTSB | |
| SCHEMBL18967517 | 0.78 | ALDH1A1 (0.48) | MAPTCASP6POLBAPEX1CTSB | |
| SCHEMBL23499978 | 0.78 | ALDH1A1 (0.50) | MAPTCASP6POLBAPEX1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101578275-A | Anilinopiperazine derivatives and methods of use thereof | SCHERING CORP (US) | 2009-11-11 | — | — | CN | disclosed |
| US-5589100-A | LIQUID CRYSTAL DISPLAY SUBSTRATES WITH ARYLAZO OR POLYARYLAZO DYES | HERCULES INCORPORATED (US) | 1996-12-31 | — | — | US | disclosed |
| US-5326865-A | Arylazo and poly(arylazo) dyes having at least one core radical selected from naphthyl or anthracyl and having at least one 2,3-dihydro-1,3-dialkyl perimidine substituent | HERCULES INCORPORATED (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0460504-B1 | Dichroic azo dyes | HERCULES INC (US) | 1994-04-27 | — | — | EP | disclosed |
| EP-0460504-A1 | Dichroic azo dyes | HERCULES INCORPORATED (US) | 1991-12-11 | — | — | EP | disclosed |