SCHEMBL9162298

SCHEMBL9162298

O=[N+]([O-])c1ccc2ccccc2c1-c1c(O)ccc2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSB P07858 2/20 0.59
MAPT P10636 5/20 0.55
CASP6 P55212 3/20 0.55
POLB P06746 1/20 0.55
APEX1 P27695 1/20 0.55
TSHR P16473 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
TP53 P04637 1/20 0.54
CYP3A4 P08684 1/20 0.54
HPGD P15428 1/20 0.54
HIF1A Q16665 1/20 0.54
ALDH1A1 P00352 2/20 0.53
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
KDM4E B2RXH2 2/20 0.51
HPRT1 P00492 1/20 0.50
CSNK2A2 P19784 1/20 0.48
CSNK2B P67870 1/20 0.48
CSNK2A1 P68400 1/20 0.48
CSNK2A3 Q8NEV1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9618737 0.84 CASP6 (0.65) CTSBMAPTCASP6POLBAPEX1
SCHEMBL8944624 0.84 MAPT (0.53) CTSBMAPTCASP6POLBAPEX1
SCHEMBL27791239 0.81 ALDH1A1 (0.50) CTSBMAPTCASP6POLBAPEX1
SCHEMBL29362162 0.80 PTPN22 (0.65) MAPTPOLBTSHRHPGDALDH1A1
SCHEMBL15400598 0.80 PTPN22 (0.65) MAPTPOLBTSHRHPGDALDH1A1
SCHEMBL29027 0.80 PTPN22 (0.65) MAPTPOLBTSHRHPGDALDH1A1
SCHEMBL6241864 0.79 ALDH1A1 (0.56) CTSBMAPTCASP6TSHRSMN1; SMN2
SCHEMBL589016 0.79 CASP6 (0.66) CTSBMAPTCASP6TSHRTP53
SCHEMBL28058443 0.79 CASP6 (0.66) CTSBMAPTCASP6TSHRTP53
SCHEMBL2115245 0.78 CASP6 (0.53) CTSBMAPTCASP6POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108658774-B Synthesis method of novel chiral nitrobinaphthol and derivatives thereof 中国科学院青岛生物能源与过程研究所 2020-11-27 CN claimed
CN-113620901-B Crown ether derived chiral 1,1 '-bi-2, 2' -naphthol, preparation method and application thereof 杭州师范大学 2023-02-10 CN disclosed
CN-113620901-A Crown ether derived chiral 1,1 '-bi-2, 2' -naphthol, preparation method and application thereof 杭州师范大学 2021-11-09 CN disclosed
CN-108658774-B Synthesis method of novel chiral nitrobinaphthol and derivatives thereof 中国科学院青岛生物能源与过程研究所 2020-11-27 CN disclosed
CN-108658774-B Synthesis method of novel chiral nitrobinaphthol and derivatives thereof 中国科学院青岛生物能源与过程研究所 2020-11-27 CN disclosed
CN-108658774-B Synthesis method of novel chiral nitrobinaphthol and derivatives thereof 中国科学院青岛生物能源与过程研究所 2020-11-27 CN disclosed
EP-0509451-B1 Improved solid electrolytic capacitors and method for manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1995-03-29 EP disclosed
US-5187650-A Having valve metal with oxide layer, conductive polymer and support electrolyte with nitro group MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1993-02-16 US disclosed
EP-0509451-A1 Improved solid electrolytic capacitors and method for manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-10-21 EP disclosed