Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 4/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944748 | 0.75 | BCAT1 (0.45) | KMT2ATSHRALDH1A1GAAMEN1 | |
| SCHEMBL7533362 | 0.74 | TSHR (0.75) | KMT2ATSHRALDH1A1ESR1HSD17B10 | |
| SCHEMBL3801964 | 0.74 | MAPK1 (0.41) | KMT2ATSHRALDH1A1GAAMMP2 | |
| SCHEMBL9589452 | 0.72 | TSHR (0.57) | KMT2ATSHRALDH1A1ESR1HSD17B10 | |
| SCHEMBL3801962 | 0.70 | TSHR (0.46) | KMT2ATSHRALDH1A1MMP2CYP2D6 | |
| SCHEMBL24385786 | 0.70 | MMP2 (0.36) | KMT2AALDH1A1CHRM4CHRM3MEN1 | |
| SCHEMBL9591172 | 0.69 | TSHR (0.63) | KMT2ATSHRALDH1A1ESR1HSD17B10 | |
| SCHEMBL24385835 | 0.69 | MGLL (0.35) | KMT2ATSHRALDH1A1MEN1MMP2 | |
| SCHEMBL24385904 | 0.69 | GAA (0.50) | KMT2ATSHRALDH1A1GAAMEN1 | |
| SCHEMBL24385815 | 0.68 | GAA (0.35) | KMT2AALDH1A1CHRM4CHRM3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578731-A | ASYMMETRICAL HYDRAZINE DERIVATIVE | CIBA-GEIGY CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| US-5554754-A | PHOTOSTABILIZERS | CIBA-GEIGY CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |
| US-5470980-A | Light stabilizers for polymers that can be grafted to polymers | CIBA-GEIGY CORPORATION (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0647626-A1 | Azadicarboxylic acid derivatives containing hindered amine moieties as polymer stabilisers | CIBA-GEIGY AG (CH) | 1995-04-12 | — | — | EP | disclosed |