Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944808 | 1.00 | NPC1 (0.33) | NPC1RAB9ADRD2KDM4E | |
| SCHEMBL8944805 | 1.00 | NPC1 (0.33) | NPC1RAB9ADRD2KDM4E | |
| SCHEMBL8040058 | 0.85 | DRD2 (0.35) | DRD2KDM4E | |
| SCHEMBL8027949 | 0.83 | USP5 (0.31) | DRD2 | |
| SCHEMBL8027953 | 0.83 | USP5 (0.31) | DRD2 | |
| SCHEMBL8027948 | 0.83 | USP5 (0.31) | DRD2 | |
| SCHEMBL8977338 | 0.83 | NPC1 (0.38) | NPC1RAB9AKDM4E | |
| SCHEMBL8977348 | 0.83 | NPC1 (0.38) | NPC1RAB9AKDM4E | |
| SCHEMBL7759933 | 0.83 | DGAT1 (0.32) | NPC1RAB9A | |
| SCHEMBL8580088 | 0.82 | AKR1C2 (0.34) | NPC1RAB9ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5560866-A | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-10-01 | — | — | US | disclosed |
| EP-0688776-A2 | Process for preparing silacyclo-hexane compounds | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-12-27 | — | — | EP | disclosed |