SCHEMBL8944937

SCHEMBL8944937

CCC1(Cc2ccc(N)cc2)CCC(c2cccc(F)c2)CC1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.43
RCOR1 Q9UKL0 1/20 0.43
CCR2 P41597 1/20 0.35
KCNH2 Q12809 1/20 0.35
MAOB P27338 2/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
TAAR1 Q96RJ0 2/20 0.34
DRD4 P21917 1/20 0.34
RIPK1 Q13546 1/20 0.33
ADAMTS5 Q9UNA0 1/20 0.33
MLYCD O95822 1/20 0.32
PARP10 Q53GL7 1/20 0.32
CCR5 P51681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8945326 0.92 KDM1A (0.40) KDM1ARCOR1CCR2KCNH2MAOB
SCHEMBL8945239 0.86 HTR2C (0.43) HTR2AHTR2CHTR2BTAAR1DRD4
SCHEMBL8945134 0.86 SIGMAR1 (0.37) DRD4
SCHEMBL8945344 0.85 KDM1A (0.39) KDM1ARCOR1CCR2KCNH2MAOB
SCHEMBL8945283 0.84 DRD2 (0.44) MAOBDRD4
SCHEMBL8945086 0.78 HTR2C (0.43) HTR2AHTR2CHTR2BDRD4ADAMTS5
SCHEMBL8945094 0.78 SIGMAR1 (0.36) KDM1AMAOBDRD4
SCHEMBL8945440 0.77 DRD2 (0.44) KDM1AMAOBDRD4
SCHEMBL8945045 0.76 DRD2 (0.42) HTR2AHTR2CHTR2BDRD4
SCHEMBL8945156 0.75 DRD1 (0.41) HTR2CDRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5501884-A Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1996-03-26 US disclosed