Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945094 | 0.91 | SIGMAR1 (0.36) | SIGMAR1NPC1RAB9ADRD2DRD3 | |
| SCHEMBL8945283 | 0.90 | DRD2 (0.44) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL8945239 | 0.88 | HTR2C (0.43) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL8944937 | 0.86 | KDM1A (0.43) | DRD4 | |
| SCHEMBL8945440 | 0.83 | DRD2 (0.44) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL8945086 | 0.79 | HTR2C (0.43) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL8945326 | 0.78 | KDM1A (0.40) | DRD2DRD4 | |
| SCHEMBL8945045 | 0.77 | DRD2 (0.42) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL8945105 | 0.77 | DRD2 (0.44) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL8945156 | 0.76 | DRD1 (0.41) | DRD2DRD3DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |