Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945012 | 0.78 | FAAH (0.50) | FAAHMGLLSSTR4SMN1; SMN2HPGD | |
| SCHEMBL8945044 | 0.78 | FAAH (0.36) | FAAHMGLLSSTR4 | |
| Hydrochloric Acid SCHEMBL8945446 | 0.77 | FAAH (0.49) | FAAHMGLLSSTR4SMN1; SMN2HPGD | |
| SCHEMBL8945315 | 0.74 | FAAH (0.56) | FAAHMGLLSSTR4CA2SMN1; SMN2 | |
| SCHEMBL8945300 | 0.74 | FAAH (0.37) | FAAHMGLLPDE10APPARGPPARD | |
| Hydrochloric Acid SCHEMBL8945205 | 0.73 | FAAH (0.55) | FAAHMGLLSSTR4CA2SMN1; SMN2 | |
| SCHEMBL8945129 | 0.70 | FAAH (0.36) | FAAHMGLLSSTR4CYP1A2CYP2C19 | |
| SCHEMBL8945197 | 0.70 | FAAH (0.47) | FAAHMGLLSSTR4SMN1; SMN2HPGD | |
| SCHEMBL8944952 | 0.68 | FAAH (0.48) | FAAHMGLLSSTR4SMN1; SMN2HPGD | |
| SCHEMBL14381397 | 0.68 | FAAH (0.66) | FAAHMGLLCA2NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |