Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.32 |
| ▸ | TUBB | P07437 | 2/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945159 | 0.83 | FAAH (0.35) | FAAHMGLLLMNACYP1A2KDM4E | |
| Oxalic Acid SCHEMBL8945224 | 0.81 | FAAH (0.34) | FAAHMGLLLMNACYP1A2KDM4E | |
| SCHEMBL8945107 | 0.81 | FAAH (0.49) | FAAHCYP1A2TSHRKDM4EALDH1A1 | |
| SCHEMBL8945254 | 0.81 | FAAH (0.34) | FAAHLMNACYP1A2CYP2D6KDM4E | |
| Hydrochloric Acid SCHEMBL8945306 | 0.81 | FAAH (0.34) | FAAHLMNACYP1A2CYP2D6KDM4E | |
| SCHEMBL8944906 | 0.81 | CYP1A2 (0.35) | FAAHLMNACYP1A2TSHRCYP2D6 | |
| Hydrochloric Acid SCHEMBL8945060 | 0.80 | FAAH (0.48) | FAAHCYP1A2TSHRKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8945170 | 0.79 | FAAH (0.38) | FAAHLMNACYP1A2TSHRHIF1A | |
| Hydrochloric Acid SCHEMBL8945351 | 0.79 | FAAH (0.34) | FAAHLMNACYP1A2HIF1AKDM4E | |
| SCHEMBL8945191 | 0.78 | KCNH2 (0.40) | LMNACYP1A2HIF1ACYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |